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非亚洲患者的静脉石性结肠炎:病例报告。

Phlebosclerotic colitis in a non-Asian patient: a case report.

机构信息

Pathology Unit, Hospital Universitario Virgen del Rocío, Seville, Spain.

Radiology Unit, Hospital Universitario Virgen del Rocío, Seville, Spain.

出版信息

J Med Case Rep. 2021 Jul 18;15(1):349. doi: 10.1186/s13256-021-02930-2.

DOI:10.1186/s13256-021-02930-2
PMID:34274012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8286582/
Abstract

BACKGROUND

Phlebosclerotic colitis is a rare condition with a high mortality. It has been seen almost exclusively in Asian patients who are ≥ 60 years old, with a slight male predominance. Although it predominantly affects the right colon and seems to be related in some cases to using natural herbal medicines, neither its etiology nor its pathogenesis are known.

CASE PRESENTATION

We present an extremely rare case of a 62-year-old Spanish white man patient of non-Asian ethnicity with no history of using natural medications, who was diagnosed with phlebosclerotic colitis of submucosal veins.

CONCLUSION

To date, this is the only case reported in Spain, and only the second reported for Europe, in the literature. Due to the nonspecific symptoms and insidious radiological findings of this disease (both in early and mild stages) as well as exclusive submucosal involvement presented here, it is necessary that the treating physician has a high level of suspicion for its diagnosis.

摘要

背景

静脉石性结肠炎是一种罕见的疾病,死亡率很高。它几乎只发生在≥60 岁的亚洲患者中,男性略占优势。虽然它主要影响右结肠,在某些情况下似乎与使用天然草药有关,但它的病因和发病机制尚不清楚。

病例介绍

我们报告了一个极其罕见的病例,一名 62 岁的西班牙白人男性,无使用天然药物的病史,被诊断为黏膜下静脉静脉石性结肠炎。

结论

迄今为止,这是在西班牙报告的首例病例,也是文献中报告的欧洲第二例病例。由于该病(无论是在早期还是轻度阶段)的非特异性症状和隐匿性放射学表现,以及这里呈现的黏膜下受累的独特性,因此有必要让治疗医生对其诊断保持高度怀疑。

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引用本文的文献

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Idiopathic mesenteric phlebosclerosis: a rare but important disease in Asian populations.特发性肠系膜静脉硬化:亚洲人群中一种罕见但重要的疾病。
Eur J Med Res. 2025 Apr 1;30(1):219. doi: 10.1186/s40001-025-02505-7.
2
Case report and literature review: Laparoscopic extended right hemicolectomy for a 55-year-old patient with idiopathic mesenteric phlebosclerosis.病例报告与文献综述:55岁特发性肠系膜静脉硬化患者的腹腔镜扩大右半结肠切除术
Front Med (Lausanne). 2024 Jul 16;11:1382475. doi: 10.3389/fmed.2024.1382475. eCollection 2024.
3
Intestinal obstruction due to idiopathic mesenteric phlebosclerosis colitis: A case report.

本文引用的文献

1
Phlebosclerosis in lower extremities veins - a systematic review.下肢静脉硬化症——一项系统评价
Vasa. 2020 Aug;49(5):349-358. doi: 10.1024/0301-1526/a000868. Epub 2020 Apr 23.
2
An unusual cause of intestinal obstruction: phlebosclerotic colitis.肠梗阻的一种罕见病因:静脉硬化性结肠炎。
Intern Emerg Med. 2020 Mar;15(2):335-336. doi: 10.1007/s11739-019-02241-x. Epub 2019 Nov 28.
3
Phlebosclerotic Colitis - An Enigma Among Ischemic Colitis.静脉硬化性结肠炎——缺血性结肠炎中的一个谜团。
特发性肠系膜静脉硬化性结肠炎所致肠梗阻:一例报告
Front Surg. 2022 Aug 17;9:969154. doi: 10.3389/fsurg.2022.969154. eCollection 2022.
4
Widespread mesenteric phlebosclerosis presenting as intestinal obstruction due to stenosis of the right-sided colon.广泛肠系膜静脉硬化症表现为右半结肠癌狭窄引起的肠梗阻。
Clin J Gastroenterol. 2022 Aug;15(4):717-721. doi: 10.1007/s12328-022-01637-1. Epub 2022 Apr 30.
J Clin Imaging Sci. 2019 May 24;9:18. doi: 10.25259/JCIS-30-2019. eCollection 2019.
4
Phlebosclerotic colitis: Our clinical experience of 25 patients in China.静脉硬化性结肠炎:我们在中国25例患者的临床经验。
Medicine (Baltimore). 2018 Oct;97(43):e12824. doi: 10.1097/MD.0000000000012824.
5
Exclusive Phlebosclerosis of Submucosal Veins Leading to Ischemic Necrosis and Perforation of the Large Bowel: First European Case.导致大肠缺血性坏死和穿孔的黏膜下静脉单纯性静脉硬化:首例欧洲病例
Case Rep Gastroenterol. 2018 Apr 13;12(1):137-142. doi: 10.1159/000488195. eCollection 2018 Jan-Apr.
6
A case of phlebosclerotic colitis.
Clin Res Hepatol Gastroenterol. 2015 Dec;39(6):651-2. doi: 10.1016/j.clinre.2015.06.013. Epub 2015 Jul 20.
7
Phlebosclerotic colitis: A case report and review of the literature.静脉硬化性结肠炎:一例病例报告及文献综述
Exp Ther Med. 2014 Mar;7(3):583-586. doi: 10.3892/etm.2014.1492. Epub 2014 Jan 20.
8
Colon ischemia: recent insights and advances.结肠缺血:最新见解与进展
Curr Gastroenterol Rep. 2010 Oct;12(5):383-90. doi: 10.1007/s11894-010-0127-y.
9
Phlebosclerotic colitis with nonsurgical treatment.
Int J Colorectal Dis. 2009 Oct;24(10):1241-2. doi: 10.1007/s00384-009-0707-1. Epub 2009 Apr 24.
10
New histologic findings in idiopathic mesenteric phlebosclerosis: clues to its pathogenesis and etiology--probably ingested toxic agent-related.特发性肠系膜静脉硬化的新组织学发现:其发病机制和病因的线索——可能与摄入的有毒物质有关。
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