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广泛肠系膜静脉硬化症表现为右半结肠癌狭窄引起的肠梗阻。

Widespread mesenteric phlebosclerosis presenting as intestinal obstruction due to stenosis of the right-sided colon.

机构信息

Department of Gastrointestinal Surgery, Tennohdai Digestive Hospital, 1-Chome 18-38 Shibasakidai, Abiko, Chiba, 270-1176, Japan.

Department of Surgery, Chiba-Ken Saiseikai Narashino Hospital, Social Welfare Organization Saiseikai Imperial Gift Foundation, 1-Chome 1-1 Izumi-cho, Narashino, Chiba, 275-8580, Japan.

出版信息

Clin J Gastroenterol. 2022 Aug;15(4):717-721. doi: 10.1007/s12328-022-01637-1. Epub 2022 Apr 30.

DOI:10.1007/s12328-022-01637-1
PMID:35489002
Abstract

Mesenteric phlebosclerosis is a rare form of intestinal ischemia characterized by thickening of the right-sided colon and calcification of the mesenteric vein. We describe the case of a 58-year-old woman admitted to our hospital because of abdominal pain and distension. An abdominal computed tomography study revealed remarkable dilatation and fluid collection of the small intestine compatible with intestinal obstruction, which was considered to be the result of stenosis of the ascending colon. The thickened wall of the cecum and ascending colon was associated with calcification of the colonic wall and mesenteric veins. Colonoscopy showed dark purple discoloration of the edematous mucosa from the splenic flexure through the hepatic flexure, at which point the colonoscope could not be advanced further because of stenosis of the ascending colon. Over 10 years previously, the patient had taken an herbal medicine containing gardenia fruit, which can cause mesenteric phlebosclerosis. An extensive colonic resection was performed after intestinal decompression. This case highlights extensive mesenteric phlebosclerosis causing intestinal obstruction from the cecum through the proximal portion of the sigmoid colon, which was treated with extensive colonic resection.

摘要

肠系膜静脉性硬纤维化是一种罕见的肠缺血形式,其特征为右半结肠增厚和肠系膜静脉钙化。我们描述了一位 58 岁女性的病例,她因腹痛和腹胀而入院。腹部 CT 研究显示小肠显著扩张和积液,符合肠梗阻的表现,考虑为升结肠狭窄所致。回盲部和升结肠的增厚壁与结肠壁和肠系膜静脉的钙化有关。结肠镜检查显示从脾曲到肝曲的水肿黏膜呈深紫色变色,此时由于升结肠狭窄,结肠镜无法进一步推进。10 多年前,该患者曾服用过一种含有栀子的草药,这可能导致肠系膜静脉性硬纤维化。在进行肠道减压后,进行了广泛的结肠切除术。本例提示广泛的肠系膜静脉性硬纤维化导致从盲肠到近端乙状结肠的肠梗阻,通过广泛的结肠切除术进行治疗。

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Clin J Gastroenterol. 2022 Aug;15(4):717-721. doi: 10.1007/s12328-022-01637-1. Epub 2022 Apr 30.
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引用本文的文献

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Extensive idiopathic mesenteric phlebosclerosis presenting as intestinal pseudo-obstruction: A case report.表现为肠道假性梗阻的广泛性特发性肠系膜静脉硬化:一例报告
World J Clin Cases. 2025 Sep 6;13(25):105028. doi: 10.12998/wjcc.v13.i25.105028.
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Idiopathic mesenteric phlebosclerosis associated with use of Chinese patent medicine: a case report and literature review.与使用中成药相关的特发性肠系膜静脉硬化:一例报告及文献复习
Front Med (Lausanne). 2025 Jul 9;12:1583341. doi: 10.3389/fmed.2025.1583341. eCollection 2025.
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Idiopathic mesenteric phlebosclerosis: a rare but important disease in Asian populations.

本文引用的文献

1
Phlebosclerotic colitis in a non-Asian patient: a case report.非亚洲患者的静脉石性结肠炎:病例报告。
J Med Case Rep. 2021 Jul 18;15(1):349. doi: 10.1186/s13256-021-02930-2.
2
Total dosage of gardenia fruit used by patients with mesenteric phlebosclerosis.患有肠系膜静脉硬化症患者使用的栀子总剂量。
BMC Complement Altern Med. 2016 Jul 11;16:207. doi: 10.1186/s12906-016-1182-1.
3
Reversible vascular occlusion of the colon.结肠可逆性血管闭塞
特发性肠系膜静脉硬化:亚洲人群中一种罕见但重要的疾病。
Eur J Med Res. 2025 Apr 1;30(1):219. doi: 10.1186/s40001-025-02505-7.
4
Drug-related: A case of idiopathic mesenteric phlebosclerosis combined with calcification of the esophageal veins.药物相关:一例特发性肠系膜静脉硬化合并食管静脉钙化。
JGH Open. 2024 Jan 17;8(1):e13027. doi: 10.1002/jgh3.13027. eCollection 2024 Jan.
Surg Gynecol Obstet. 1963 Jan;116:53-60.