Department of Cardiovascular Surgery, Zhongshan Hospital, Fudan University.
Department of Echocardiography, Zhongshan Hospital, Fudan University.
Int Heart J. 2021 Jul 30;62(4):764-770. doi: 10.1536/ihj.20-765. Epub 2021 Jul 17.
Left atrial appendage (LAA) has been found to be associated with the occurrence of thromboembolism in patients with nonvalvular atrial fibrillation (NVAF). Stapling exclusion of LAA during surgical ablation could be an alternative to oral anticoagulation for NVAF patients. However, its safety and efficacy have rarely been examined. Thus, in this study, we aimed to evaluate the safety and efficacy of a powered surgical stapler for LAA resection during ablation for patients with NVAF.Adult patients with NVAF undergoing stapler surgery were included in this study. LAAs of patients were cut off using a powered surgical stapler. Intraoperative transesophageal echocardiogram (TEE) was applied before and after the operation. Each patient received anticoagulant therapy for 2 months after surgery and was regularly followed up by appointment or via telephone call. Patients would undergo physical examinations, echocardiography, and 24-hour dynamic electrocardiogram in a local or in our hospital to determine whether there was a recurrence of atrial fibrillation (AF) or thromboembolism caused by AF.In total, 124 patients were included in this study (male: 88 (71.0%); mean age: 62.3 years). Blood loss was less than 100 mL in all patients with no operative complications or hospital deaths. Moreover, 119 (96.0%) follow-up data were collected, with a mean period of 27.4 months. All patients discontinued oral anticoagulants 2 months after their operation. As per our findings, AF recurred in 23 patients (18.5%), with an average of 9.1 months after surgery. No patients were diagnosed with thromboembolism related to AF.Stapling exclusion of LAA during surgical ablation could safely and completely resect the LAA. The effect of thrombus prevention was deemed satisfactory.
左心耳(LAA)已被发现与非瓣膜性心房颤动(NVAF)患者血栓栓塞的发生有关。在外科消融过程中使用缝合器排除 LAA 可能是 NVAF 患者替代口服抗凝治疗的一种选择。然而,其安全性和疗效很少被检查。因此,在这项研究中,我们旨在评估在 NVAF 患者消融过程中使用电动手术缝合器切除 LAA 的安全性和有效性。
这项研究纳入了接受缝合器手术的 NVAF 成年患者。使用电动手术缝合器切断患者的 LAA。在手术前后应用术中经食管超声心动图(TEE)。术后所有患者接受抗凝治疗 2 个月,并通过预约或电话定期随访。患者将在当地或我院进行体格检查、超声心动图和 24 小时动态心电图检查,以确定是否有房颤(AF)复发或由 AF 引起的血栓栓塞。
共有 124 例患者纳入本研究(男性:88 例(71.0%);平均年龄:62.3 岁)。所有患者的出血量均少于 100mL,无手术并发症或院内死亡。此外,收集了 119 例(96.0%)的随访数据,平均随访时间为 27.4 个月。所有患者在术后 2 个月均停止口服抗凝治疗。根据我们的发现,23 例患者(18.5%)出现 AF 复发,平均术后 9.1 个月。无患者被诊断为与 AF 相关的血栓栓塞。
外科消融过程中使用缝合器排除 LAA 可安全且完全切除 LAA。预防血栓的效果令人满意。