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Long-lived immunity to genetically detoxified pertussis vaccines.对基因解毒百日咳疫苗的长期免疫力。
EClinicalMedicine. 2021 Jul 6;37:101014. doi: 10.1016/j.eclinm.2021.101014. eCollection 2021 Jul.
2
Genetically detoxified pertussis toxin induces superior antigen specific CD4 T cell responses compared to chemically detoxified pertussis toxin.基因解毒百日咳毒素比化学解毒百日咳毒素诱导更优的抗原特异性 CD4 T 细胞应答。
Hum Vaccin Immunother. 2019;15(5):1167-1170. doi: 10.1080/21645515.2019.1565270. Epub 2019 Mar 19.
3
Genetically detoxified pertussis toxin (PT-9K/129G): implications for immunization and vaccines.基因解毒百日咳毒素(PT-9K/129G):对免疫接种和疫苗的意义
Expert Rev Vaccines. 2014 Oct;13(10):1191-204. doi: 10.1586/14760584.2014.942641. Epub 2014 Sep 3.
4
The vaccine containing recombinant pertussis toxin induces early and long-lasting protection.含有重组百日咳毒素的疫苗可诱导早期且持久的保护作用。
Biologicals. 1999 Jun;27(2):99-102. doi: 10.1006/biol.1999.0189.
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Acellular pertussis vaccines containing genetically detoxified pertussis toxin induce long-lasting humoral and cellular responses in adults.含有基因解毒百日咳毒素的无细胞百日咳疫苗可在成人中诱导持久的体液和细胞免疫反应。
Vaccine. 1997 Aug;15(11):1218-24. doi: 10.1016/s0264-410x(97)00023-6.
6
A phase I, randomized, controlled, dose-ranging study of investigational acellular pertussis (aP) and reduced tetanus-diphtheria-acellular pertussis (TdaP) booster vaccines in adults.一项在成人中研究新型无细胞百日咳(aP)和减少破伤风-白喉-无细胞百日咳(TdaP)加强疫苗的 I 期、随机、对照、剂量范围研究。
Hum Vaccin Immunother. 2018 Jan 2;14(1):45-58. doi: 10.1080/21645515.2017.1385686. Epub 2017 Nov 27.
7
Reactivating Immunity Primed by Acellular Pertussis Vaccines in the Absence of Circulating Antibodies: Enhanced Bacterial Control by TLR9 Rather Than TLR4 Agonist-Including Formulation.无血清抗体存在时,非细胞百日咳疫苗激发的免疫再激活:TLR9 激动剂而非 TLR4 激动剂配方增强细菌控制。
Front Immunol. 2019 Jul 3;10:1520. doi: 10.3389/fimmu.2019.01520. eCollection 2019.
8
Novel approaches to reactivate pertussis immunity.新型百日咳免疫激活方法。
Expert Rev Vaccines. 2022 Dec;21(12):1787-1797. doi: 10.1080/14760584.2022.2149499. Epub 2022 Nov 23.
9
Phase I clinical trial of an acellular pertussis vaccine composed of genetically detoxified pertussis toxin combined with FHA and 69 kDa.由基因解毒百日咳毒素与丝状血凝素(FHA)及69千道尔顿蛋白组合而成的无细胞百日咳疫苗的I期临床试验。
Vaccine. 1991 Oct;9(10):741-5. doi: 10.1016/0264-410x(91)90290-m.
10
Diphtheria-tetanus-acellular pertussis vaccine adsorbed (Triacelluvax; DTaP3-CB): a review of its use in the prevention of Bordetella pertussis infection.吸附白喉-破伤风-无细胞百日咳疫苗(Triacelluvax;DTaP3-CB):其用于预防百日咳博德特氏菌感染的综述
Paediatr Drugs. 2000 Mar-Apr;2(2):139-59. doi: 10.2165/00148581-200002020-00007.

本文引用的文献

1
Antibody persistence 2 and 3 years after booster vaccination of adolescents with recombinant acellular pertussis monovalent aP or combined TdaP vaccines.青少年接种重组无细胞百日咳单价aP疫苗或联合Tdap疫苗加强免疫2年和3年后的抗体持久性
EClinicalMedicine. 2021 Jun 23;37:100976. doi: 10.1016/j.eclinm.2021.100976. eCollection 2021 Jul.
2
Pertussis vaccine effectiveness and duration of protection - A systematic review and meta-analysis.百日咳疫苗有效性和保护持续时间的系统评价和荟萃分析。
Vaccine. 2021 May 27;39(23):3120-3130. doi: 10.1016/j.vaccine.2021.04.032. Epub 2021 Apr 30.
3
Genetically detoxified pertussis toxin displays near identical structure to its wild-type and exhibits robust immunogenicity.遗传解毒的百日咳毒素显示出与其野生型几乎相同的结构,并表现出强大的免疫原性。
Commun Biol. 2020 Aug 5;3(1):427. doi: 10.1038/s42003-020-01153-3.
4
Neutralization of pertussis toxin by a single antibody prevents clinical pertussis in neonatal baboons.单种抗体中和百日咳毒素可预防新生狨猴发生临床型百日咳。
Sci Adv. 2020 Feb 5;6(6):eaay9258. doi: 10.1126/sciadv.aay9258. eCollection 2020 Feb.
5
Antibody persistence after vaccination of adolescents with monovalent and combined acellular pertussis vaccines containing genetically inactivated pertussis toxin: a phase 2/3 randomised, controlled, non-inferiority trial.青少年接种单价和结合无细胞百日咳疫苗(含基因失活百日咳毒素)后的抗体持久性:一项 2/3 期随机、对照、非劣效性试验。
Lancet Infect Dis. 2018 Nov;18(11):1260-1268. doi: 10.1016/S1473-3099(18)30375-X. Epub 2018 Sep 25.
6
An update of the global burden of pertussis in children younger than 5 years: a modelling study.全球 5 岁以下儿童百日咳负担的更新:一项建模研究。
Lancet Infect Dis. 2017 Sep;17(9):974-980. doi: 10.1016/S1473-3099(17)30390-0. Epub 2017 Jun 13.
7
Asymptomatic transmission and the resurgence of Bordetella pertussis.百日咳博德特氏菌的无症状传播及再度流行
BMC Med. 2015 Jun 24;13:146. doi: 10.1186/s12916-015-0382-8.
8
Acellular vaccines for preventing whooping cough in children.用于预防儿童百日咳的无细胞疫苗。
Cochrane Database Syst Rev. 2012 Mar 14(3):CD001478. doi: 10.1002/14651858.CD001478.pub5.
9
Clinical practice. Pertussis--not just for kids.临床实践。百日咳——并非只关乎儿童。
N Engl J Med. 2005 Mar 24;352(12):1215-22. doi: 10.1056/NEJMcp041025.
10
Acellular pertussis vaccine composed of genetically inactivated pertussis toxin: safety and immunogenicity in 12- to 24- and 2- to 4-month-old children.由基因灭活百日咳毒素组成的无细胞百日咳疫苗:12至24月龄及2至4月龄儿童的安全性和免疫原性。
J Pediatr. 1992 May;120(5):680-5. doi: 10.1016/s0022-3476(05)80227-6.

Long-lived immunity to genetically detoxified pertussis vaccines.

作者信息

Locht Camille

机构信息

U1019-UMR 8204-CIIL-Center for Infection and Immunity of Lille, Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, Lille F-59000, France.

出版信息

EClinicalMedicine. 2021 Jul 6;37:101014. doi: 10.1016/j.eclinm.2021.101014. eCollection 2021 Jul.

DOI:10.1016/j.eclinm.2021.101014
PMID:34278279
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8267544/
Abstract
摘要