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支架辅助弹簧圈栓塞治疗椎基底动脉夹层动脉瘤:单中心研究。

Overlapping stent-assisted coil embolization for vertebrobasilar dissecting aneurysms: a single-center study.

机构信息

Queen Mary College, Nanchang University, Nanchang, Jiang Xi Province, People`s Republic of China.

Department of Neurosurgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People's Republic of China.

出版信息

Neurol Res. 2021 Sep;43(9):701-707. doi: 10.1080/01616412.2021.1922172. Epub 2021 Jul 18.

Abstract

Effective treatment strategies for vertebrobasilar dissecting aneurysms (VBDAs) remain controversial due to their high morbidity and mortality. The aim of the present study was to evaluate the efficacy of overlapping stent-assisted coil embolization (OSCE) in VBDA patients. A total of 42 patients with VBDA were retrospectively examined by OSCE from May 2015 to August 2019. Patients' clinical and radiological parameters were assessed at discharge and during interim follow-up. Safety, technical feasibility and follow-up clinical and imaging observations for therapy were also evaluated retrospectively. The average age of the 42 patients who underwent OSCE was 54 years (range 33 to 74 years). Overlapping stents were successfully implanted in all patients after coil embolism. Overall clinical results were effective (score on a modified Rankin scale from 0 to 2) in all patients. In the meantime, all patients had favorable outcomes when evaluating telephone calls or digital subtractive angiography (DSA) imaging. Among 42 patients, one patient died due to a perioperative rupture. All the remaining 41 patients had a good prognosis during the follow-up telephone call, with a median follow-up of 28 months (range, 2 to 55 months). The total number of DSA recurrences was 20. Subsequent DSA results showed that all aneurysms were completely occluded while in only one case the parent artery of the aneurysm was completely closed. OSCE in VBDAs patients is safe and effective. This technique showed favorable results in clinical and imaging follow-ups for non-ruptured and ruptured VBDAs.

摘要

重叠支架辅助弹簧圈栓塞术治疗椎基底动脉夹层动脉瘤的疗效分析

由于椎基底动脉夹层动脉瘤(vertebrobasilar dissecting aneurysms,VBDAs)患者的高发病率和死亡率,有效的治疗策略仍存在争议。本研究旨在评估重叠支架辅助弹簧圈栓塞术(overlapping stent-assisted coil embolization,OSCE)治疗 VBDA 的疗效。

回顾性分析 2015 年 5 月至 2019 年 8 月采用 OSCE 治疗的 42 例 VBDA 患者的临床和影像学资料。出院时及随访期间评估患者的临床和影像学参数。回顾性评估治疗的安全性、技术可行性和随访的临床及影像学观察结果。

42 例行 OSCE 的患者平均年龄 54 岁(3374 岁)。所有患者在弹簧圈栓塞后均成功植入重叠支架。所有患者的总体临床结果均有效(改良 Rankin 量表评分为 02 分)。同时,所有患者在电话或数字减影血管造影(digital subtractive angiography,DSA)评估中均有良好的预后。42 例患者中,1 例患者因围手术期破裂死亡。所有其余 41 例患者在随访电话中预后良好,中位随访时间为 28 个月(2~55 个月)。DSA 复发总数为 20 例。随后的 DSA 结果显示所有动脉瘤完全闭塞,仅 1 例动脉瘤的载瘤动脉完全闭塞。

在 VBDA 患者中,OSCE 是安全有效的。该技术在非破裂和破裂 VBDA 的临床和影像学随访中均取得了良好的结果。

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