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负载姜黄素、白藜芦醇和琉璃苣籽油的喷雾干燥纳米乳剂:两种不同改性淀粉作为包封材料的作用。

Spray dried nanoemulsions loaded with curcumin, resveratrol, and borage seed oil: The role of two different modified starches as encapsulating materials.

作者信息

Rehman Abdur, Tong Qunyi, Jafari Seid Mahdi, Korma Sameh A, Khan Imran Mahmood, Mohsin Ali, Manzoor Muhammad Faisal, Ashraf Waqas, Mushtaq Bilal Sajid, Zainab Saadia, Cacciotti Ilaria

机构信息

State Key Laboratory of Food Science and Technology, Jiangnan University, Jiangsu, Wuxi 214122, China; Collaborative Innovation Centre of Food Safety and Quality Control, Jiangsu Province, China.

State Key Laboratory of Food Science and Technology, Jiangnan University, Jiangsu, Wuxi 214122, China; Collaborative Innovation Centre of Food Safety and Quality Control, Jiangsu Province, China.

出版信息

Int J Biol Macromol. 2021 Sep 1;186:820-828. doi: 10.1016/j.ijbiomac.2021.07.076. Epub 2021 Jul 16.

Abstract

Recently, food industries are directing on the promotion of innovative food matrices fortified with bioactive compounds in order to enhance the consumer's health. Octenyl succinic anhydride modified starches (OSA-MS) such as Hi-cap100 (HCP) and purity gum 2000 (PUG) were used to fabricate emulsions co-entrapped with borage seed oil (BSO), resveratrol (RES) and curcumin (CUR), which were further spray dried to obtain powders. The fabricated microcapsules loaded with BSO, RES, and CUR displayed excellent dissolution performance, high encapsulation efficiency (≈93.05%) as well as semi-spherical shape, revealed via scanning electron microscopy (SEM). We also evaluated the impact of storage time (4 weeks) and temperature (40 °C) on the physicochemical characterization of OSA-MS coated microcapsules. Microcapsules coated with HCP exhibited greater oxidative stability, lower water activity and moisture contents rather than PUG coated microcapsules during storage because of its good film-forming properties. Addition of CUR enhanced the oxidative stability and retention of bioactive compounds. HCP microcapsules loaded with BSO + RES + CUR presented supreme retention of RES (70.32%), CUR 81.6% and γ-linolenic acid (≈ 96%). Our findings showed that CUR acted as an antioxidant agent; also, lower molecular weight OSA-MS as wall material could be used for the entrapment of bioactive compounds and promotion of innovative food products.

摘要

最近,食品行业致力于推广添加生物活性化合物的创新型食品基质,以增进消费者健康。使用辛烯基琥珀酸酐改性淀粉(OSA-MS),如Hi-cap100(HCP)和纯度胶2000(PUG),来制备包埋有琉璃苣籽油(BSO)、白藜芦醇(RES)和姜黄素(CUR)的乳液,然后将其进一步喷雾干燥以获得粉末。通过扫描电子显微镜(SEM)显示,制备的负载BSO、RES和CUR的微胶囊具有优异的溶解性能、高包封率(约93.05%)以及半球形形状。我们还评估了储存时间(4周)和温度(40°C)对OSA-MS包衣微胶囊理化特性的影响。在储存过程中,由于其良好的成膜性能,HCP包衣的微胶囊比PUG包衣的微胶囊表现出更高的氧化稳定性、更低的水分活度和水分含量。添加CUR增强了生物活性化合物的氧化稳定性和保留率。负载BSO + RES + CUR的HCP微胶囊对RES的保留率最高(70.32%),CUR为81.6%,γ-亚麻酸(约96%)。我们的研究结果表明,CUR起到了抗氧化剂的作用;此外,低分子量的OSA-MS作为壁材可用于包埋生物活性化合物并促进创新食品的开发。

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