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淀粉基功能性食品纳米微胶囊递送系统的制备及其控释特性。

Preparation of starch-based functional food nano-microcapsule delivery system and its controlled release characteristics.

作者信息

Tian Shuangqi, Xue Xing'ao, Wang Xinwei, Chen Zhicheng

机构信息

College of Food Science and Technology, Henan University of Technology, Zhengzhou, China.

出版信息

Front Nutr. 2022 Aug 15;9:982370. doi: 10.3389/fnut.2022.982370. eCollection 2022.

Abstract

Most of the functional substances in food are absorbed in the small intestine, but before entering the small intestine, the strong acid and enzymes in the stomach limit the amount that can reach the small intestine. Therefore, in this paper, to develop a delivery system for functional food ingredients, maintain the biological activity of the ingredients, and deliver them to the target digestive organs, preparation of starch-based functional food nano-microcapsule delivery system and its controlled release characteristics were reviewed. Embedding unstable food active ingredients in starch-based nano-microcapsules can give the core material excellent stability and certain functional effects. Starch-based wall materials refer to a type of natural polymer material that uses starch or its derivatives to coat fat-soluble components with its hydrophobic cavities. The preparation methods of starch-based wall materials mainly include spray drying, extrusion, freeze drying, ultra-high pressure, coagulation, fluidized bed coating, molecular inclusion, chemical, and enzymic methods. The controlled release of functional food can be achieved by preparing starch-based nano-microcapsules to encapsulate the active agents. It has been reported that that compared with traditional embedding agents such as gelatin, acacia gum, and xanthan gum, starch-based functional food nano-microcapsule delivery system had many good properties, including improving antioxidant capacity, bioavailability, probiotics, and concealing bad flavors. From this review, we can learn which method should be chosen to prepare starch-based functional food nano-microcapsule delivery system and understand the mechanism of controlled release.

摘要

食物中的大多数功能性物质在小肠中被吸收,但在进入小肠之前,胃中的强酸和酶会限制能够到达小肠的量。因此,本文综述了淀粉基功能性食品纳米微胶囊递送系统的制备及其控释特性,旨在开发一种功能性食品成分递送系统,保持成分的生物活性,并将其递送至目标消化器官。将不稳定的食品活性成分包埋在淀粉基纳米微胶囊中,可以赋予核心材料优异的稳定性和一定的功能效果。淀粉基壁材是指一类天然高分子材料,它利用淀粉或其衍生物,通过其疏水空腔包覆脂溶性成分。淀粉基壁材的制备方法主要包括喷雾干燥、挤压、冷冻干燥、超高压、凝聚、流化床包衣、分子包合、化学和酶法。通过制备淀粉基纳米微胶囊来包封活性剂,可以实现功能性食品的控释。据报道,与明胶、阿拉伯胶和黄原胶等传统包埋剂相比,淀粉基功能性食品纳米微胶囊递送系统具有许多良好的性能,包括提高抗氧化能力、生物利用度、益生菌和掩盖不良风味。通过这篇综述,我们可以了解制备淀粉基功能性食品纳米微胶囊递送系统应选择哪种方法,并了解其控释机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c790/9421261/7d3a2aede289/fnut-09-982370-g0001.jpg

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