Ingebretson M C, Pucino F, Beck C L, Strommen G L, McAskill A C, Rao U P, Almazan A N
Veterans Administration Medical Center, Fargo, ND.
Drug Intell Clin Pharm. 1987 Oct;21(10):796-7. doi: 10.1177/106002808702101006.
Morphine sulfate is the narcotic analgesic most commonly used for pain treatment in terminally ill patients. This case report demonstrates a new method of morphine administration. A 56-year-old terminally ill cancer patient with severe pain from metastatic adenocarcinoma of the lung required continuous nasogastric feeding and around-the-clock narcotic analgesics. The patient was safely and effectively converted from a continuous intravenous morphine infusion to continuous nasogastric morphine-enteral feedings. This method of administration may benefit patients receiving continuous enteral tube feedings who either require high-dose morphine therapy or are unable to use the oral administration route.
硫酸吗啡是晚期患者疼痛治疗中最常用的麻醉性镇痛药。本病例报告展示了一种新的吗啡给药方法。一名56岁晚期肺癌转移性腺癌患者因剧痛需要持续鼻饲和全天候麻醉性镇痛药。该患者从持续静脉输注吗啡安全有效地转换为持续鼻饲吗啡 - 肠内营养。这种给药方法可能使接受持续肠内管饲且需要高剂量吗啡治疗或无法采用口服给药途径的患者受益。