Genzor Samuel, Prasko Jan, Vanek Jakub, Asswad Amjad Ghazal, Nadjarpour Shayan, Sova Milan
Department of Respiratory Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech Republic.
Department of Psychiatry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022 Dec;166(4):441-446. doi: 10.5507/bp.2021.041. Epub 2021 Jul 2.
Continuous positive airway pressure (CPAP) is the most effective therapy for obstructive sleep apnoea syndrome (OSAS). Long-term adherence is necessary; however, it may be widely variable based on current literature, where the predicting factors are also not well defined. The aim of this study was to assess ten-year adherence to CPAP and to define factors influencing it.
In total, 107 patients (91 males) were enrolled in this study, with an average age of 53.5 years (SD 10.1), with CPAP therapy being indicated (Apnoea-Hypopnoea Index - AHI > 15). Anthropometric and social status data have been obtained as well as the average use of CPAP through device memory.
Sufficient adherence (> 4 h per night) was found in 57% of patients in the first year with no subsequent significant change during the next 9 years. Adherence correlated significantly with the severity of OSAS - AHI (r = 0.321 over 5 years) and Epworth Sleepiness Scale (r = 0.317 over ten years) but did not correlate with the pressure used or the age of the patient. No statistically significant differences have been found between the sexes, the different mask groups, or the social status groups.
Good adherence to CPAP therapy in OSAS patients is essential. According to our results, patients with more severe OSAS or more severe sleepiness seem to have better adherence.
持续气道正压通气（CPAP）是治疗阻塞性睡眠呼吸暂停综合征（OSAS）最有效的方法。长期坚持使用是必要的；然而，根据目前的文献，其依从性可能差异很大，且预测因素也未明确界定。本研究的目的是评估CPAP的十年依从性并确定影响因素。
本研究共纳入107例患者（91例男性），平均年龄53.5岁（标准差10.1），均有CPAP治疗指征（呼吸暂停低通气指数 - AHI>15）。收集了人体测量和社会状况数据以及通过设备内存记录的CPAP平均使用情况。
第一年57%的患者依从性良好（每晚使用>4小时），在接下来的9年中无显著变化。依从性与OSAS的严重程度 - AHI（5年期间r = 0.321）和爱泼华嗜睡量表（10年期间r = 0.317）显著相关，但与使用的压力或患者年龄无关。在性别、不同面罩组或社会状况组之间未发现统计学上的显著差异。
OSAS患者对CPAP治疗的良好依从性至关重要。根据我们的结果，OSAS更严重或嗜睡更严重的患者似乎依从性更好。
