Peker Yüksel, Balcan Baran
Department of Pulmonary Medicine, School of Medicine, Koc University, Istanbul, Turkey.
Department of Clinical Sciences, Respiratory Medicine and Allergology, Faculty of Medicine, Lund University, Lund, Sweden.
J Thorac Dis. 2018 Dec;10(Suppl 34):S4262-S4279. doi: 10.21037/jtd.2018.11.48.
Obstructive sleep apnea is a common disorder with increased risk for cardiovascular morbidity and mortality. The first choice of treatment of obstructive sleep apnea is continuous positive airway pressure, which reduces excessive daytime sleepiness and improves quality of life in sleep clinic cohorts. Nevertheless, the majority of patients with cardiovascular disease and concomitant obstructive sleep apnea do not report daytime sleepiness, and adherence to treatment is insufficient particularly in this group. The current article aims to give an updated overview of the impact of continuous positive airway pressure therapy on cardiovascular outcomes mainly based on the observational studies and the recent randomized controlled trials.
阻塞性睡眠呼吸暂停是一种常见疾病,会增加心血管疾病发病和死亡风险。阻塞性睡眠呼吸暂停的首选治疗方法是持续气道正压通气,这可减轻日间过度嗜睡,并改善睡眠门诊队列中的生活质量。然而,大多数患有心血管疾病并伴有阻塞性睡眠呼吸暂停的患者并未报告有日间嗜睡情况,而且尤其是在这一群体中,治疗依从性不足。本文旨在主要基于观察性研究和近期的随机对照试验,对持续气道正压通气治疗对心血管结局的影响给出最新综述。