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计算流体动力学模型揭示了气管发育过程中的非线性气道应力。

Computational Fluid Dynamic Modeling Reveals Nonlinear Airway Stress during Trachea Development.

机构信息

Department of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, OH.

Center for Surgical Outcomes Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH.

出版信息

J Pediatr. 2021 Nov;238:324-328.e1. doi: 10.1016/j.jpeds.2021.07.038. Epub 2021 Jul 18.

DOI:10.1016/j.jpeds.2021.07.038
PMID:34284034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8551055/
Abstract

Normative trachea dimensions and aerodynamic information during development was collected to establish clinical benchmarks and showed that airway development seems to outpace respiratory demands. Infants and toddlers' trachea exhibit higher aerodynamic stress that significantly decreases by teenage years. This implies large airway pathology in younger children may have a more substantial clinical impact.

摘要

收集了发育过程中的正常气管尺寸和空气动力学信息,以建立临床基准,并表明气道发育似乎超过了呼吸需求。婴儿和幼儿的气管表现出更高的空气动力学压力,这种压力在青少年时期显著降低。这意味着年幼儿童的大气道疾病可能具有更大的临床影响。

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The Application of Computational Fluid Dynamics in the Evaluation of Laryngotracheal Pathology.计算流体动力学在喉气管病理学评估中的应用。
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Paediatr Anaesth. 2018 Jan;28(1):13-22. doi: 10.1111/pan.13281. Epub 2017 Nov 17.
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Computational modeling and validation of human nasal airflow under various breathing conditions.不同呼吸条件下人体鼻腔气流的计算建模与验证
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Cricoid and left bronchial diameter in the pediatric population.儿科人群的环状软骨和左支气管直径。
Paediatr Anaesth. 2016 Jun;26(6):608-12. doi: 10.1111/pan.12896. Epub 2016 Apr 9.
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