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Serial Circulating Tumor DNA Detection Using a Personalized, Tumor-Informed Assay in Esophageal Adenocarcinoma Patients Following Resection.

作者信息

Ococks Emma, Sharma Shruti, Ng Alvin Wei Tian, Aleshin Alexey, Fitzgerald Rebecca C, Smyth Elizabeth

机构信息

Medical Research Council Cancer Unit, Hutchison/Medical Research Council Research Centre, University of Cambridge, Cambridge, United Kingdom.

Research and Development Department, Natera, Incorporated, San Carlos, California.

出版信息

Gastroenterology. 2021 Nov;161(5):1705-1708.e2. doi: 10.1053/j.gastro.2021.07.011. Epub 2021 Jul 18.

DOI:10.1053/j.gastro.2021.07.011
PMID:34284036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8586817/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1ba/8586817/c5c1a9403bde/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1ba/8586817/f9abbcb13736/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1ba/8586817/c5c1a9403bde/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1ba/8586817/f9abbcb13736/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1ba/8586817/c5c1a9403bde/fx1.jpg

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本文引用的文献

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Longitudinal tracking of 97 esophageal adenocarcinomas using liquid biopsy sampling.采用液体活检取样对 97 例食管腺癌进行纵向跟踪。
Ann Oncol. 2021 Apr;32(4):522-532. doi: 10.1016/j.annonc.2020.12.010. Epub 2021 Jan 7.
2
Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer.循环肿瘤 DNA 分析作为 III 期结肠癌辅助治疗复发风险和获益的标志物。
JAMA Oncol. 2019 Dec 1;5(12):1710-1717. doi: 10.1001/jamaoncol.2019.3616.
3
Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial.
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Nat Commun. 2025 Jul 24;16(1):6815. doi: 10.1038/s41467-025-62056-7.
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Feasibility of Personalized and Tumor-Informed Circulating Tumor DNA Assay for Early Recurrence Detection in Patients With Hepatocellular Carcinoma.个性化且基于肿瘤信息的循环肿瘤DNA检测用于肝细胞癌患者早期复发检测的可行性
JCO Precis Oncol. 2025 Jul;9:e2400934. doi: 10.1200/PO-24-00934. Epub 2025 Jul 2.
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Multi-Centered Pre-Treatment CT-Based Radiomics Features to Predict Locoregional Recurrence of Locally Advanced Esophageal Cancer After Definitive Chemoradiotherapy.基于多中心治疗前CT的影像组学特征预测局部晚期食管癌根治性放化疗后局部区域复发
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