Leibniz-Institut für Polymerforschung Dresden, Hohe Straße 6, D-01069 Dresden, Germany.
Technische Universität Dresden, D-01069 Dresden, Germany.
Chem Commun (Camb). 2021 Aug 12;57(65):8019-8022. doi: 10.1039/d1cc03422g.
Feedback-controlled detection of subtle changes of extracellular biomolecules as known from cells is also needed in protocells. Artificial organelles, located in protocells, detect the small variation in pH which is triggered by different amounts of invading glucose, converted by glucose-oxidase into gluconic acid. The approach paves the way for using pH fluctuations-detecting artificial organelles in the lumen of protocells.
原核细胞也需要反馈控制来检测细胞外生物分子的细微变化。位于原核细胞内的人工细胞器可以检测到由于不同数量的入侵葡萄糖而引起的 pH 值的微小变化，葡萄糖氧化酶将葡萄糖转化为葡萄糖酸。该方法为在原核细胞腔中使用 pH 波动检测人工细胞器铺平了道路。
