蛋白质体上的多功能和可编程调控界面反应
Multifunctional and Programmable Modulated Interface Reactions on Proteinosomes.
机构信息
MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, The Key Laboratory of Microsystems and Microstructures Manufacturing, Ministry of Education, School of Chemistry and Chemical Engineering , Harbin Institute of Technology , Harbin 150001 , China.
The First Affiliated Hospital of Zhengzhou University , 40 Daxue Road , Zhengzhou 450052 , China.
出版信息
ACS Appl Mater Interfaces. 2018 Nov 7;10(44):38565-38573. doi: 10.1021/acsami.8b11216. Epub 2018 Oct 26.
A multiresponsive microcapsule has been synthesized by incorporating photoswitchable spiropyran units and the thermoresponsive monomer N-isopropylacrylamide into membrane lumens. By using functionalized light or thermoresponsive groups, this multifunctional microcapsule can modulate programmed release and interface reactions between lipase and fluorescein diacetate, alkaline phosphatase and fluorescein diphosphate, and others. Exposing this multifunctional microcapsule in a programmed controlled way allowed us to develop schematics to understand complicated interface interactions on protocells.
一种多响应性微胶囊已经通过将光致变色螺吡喃单元和温敏单体 N-异丙基丙烯酰胺整合到膜腔中合成。通过使用功能化的光或温敏基团，这种多功能微胶囊可以调节脂肪酶和荧光素二乙酸酯、碱性磷酸酶和荧光素二磷酸酯之间的程序释放和界面反应，等等。以程序化的方式暴露这种多功能微胶囊，使我们能够开发出方案来理解原细胞上复杂的界面相互作用。
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