通过精子传递跨代表观遗传信息：精子不仅为新生命提供了一半的基因组；它们似乎还通过表观遗传修饰传递额外的信息。
Transgenerational epigenetic information through the sperm: Sperm cells not just merely supply half of the genome for new life; they also seem to transmit additional information via epigenetic modifications.
机构信息
Department of Developmental Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Japan.
出版信息
EMBO Rep. 2021 Aug 4;22(8):e53539. doi: 10.15252/embr.202153539. Epub 2021 Jul 20.
Abstract
The biological cause for the increase in Autism Spectrum Disorder may be fathers' older age and the epigenetic marks it leaves on sperm cells.
摘要
自闭症谱系障碍增加的生物学原因可能是父亲年龄较大以及它在精子细胞上留下的表观遗传标记。
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本文引用的文献
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Nat Med. 2020 Jan;26(1):143-150. doi: 10.1038/s41591-019-0711-0. Epub 2019 Dec 23.
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