Oral Surgery Resident, Department of Dentistry, Vita-Salute San Raffaele University, Milan, Italy.
BioEngineering, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Clin Exp Dent Res. 2021 Dec;7(6):1002-1013. doi: 10.1002/cre2.469. Epub 2021 Jul 20.
This study aimed to assess the prevalence of peri-implantitis in human immunodeficiency virus (HIV)-positive patients and the presence of a possible correlation between the immunological profile and serological values, of peri-implantitis, and of possible differences between all-on-4 and single crown/bridge prostheses.
This retrospective study included 58 adult HIV-positive patients (222 implants) with either all-in-4 prostheses or single crowns/bridges on at least one dental implant loaded for more than a year who were followed for 3 year (mean follow-up). Data pertaining to the probing pocket depth (PPD), bleeding on probing, and immunological and systemic profile were collected.
Patients with single crown/bridge implant rehabilitation showed higher prevalence of peri-implantitis (34%) than patients with all-on-4 rehabilitation (0%) (p = 0.012). Patients with all-on-4 rehabilitation were significantly older than those with single crowns/bridges (p = 0.004). Patients with peri-implantitis had implants for a significantly longer duration than those without (p = 0.001), implying that the probability of peri-implantitis increases as the age of implant increases.
The prevalence of peri-implantitis was 26% in the HIV-positive patients population. No correlation was found between patients' immunological and serological factors and peri-implantitis. The most important risk factor for peri-implantitis and mucositis was implant age.
本研究旨在评估人类免疫缺陷病毒（HIV）阳性患者中种植体周围炎的患病率，以及免疫状况和血清学值与种植体周围炎之间是否存在相关性，同时评估全口种植即刻负重（All-on-4）和单冠/桥修复体之间是否存在差异。
本回顾性研究纳入了 58 名成年 HIV 阳性患者（222 枚种植体），所有患者均至少有一枚种植体在植入 1 年以上后负载全口种植即刻负重或单冠/桥修复体，随访 3 年（平均随访时间）。收集了探诊袋深度（PPD）、探诊出血、免疫和全身状况等数据。
单冠/桥种植体修复患者的种植体周围炎患病率（34%）高于全口种植即刻负重修复患者（0%）（p=0.012）。全口种植即刻负重修复患者的年龄明显大于单冠/桥修复患者（p=0.004）。患有种植体周围炎的患者的种植体使用时间明显长于无种植体周围炎的患者（p=0.001），这表明种植体周围炎的概率随着种植体年龄的增加而增加。
HIV 阳性患者中种植体周围炎的患病率为 26%。患者的免疫和血清学因素与种植体周围炎之间没有相关性。种植体年龄是种植体周围炎和黏膜炎的最重要危险因素。
