Perry Thomas A, Dando Charlotte, Spector Tim D, Hart Deborah J, Bowen Catherine, Arden Nigel
University of Oxford, Oxford, United Kingdom.
University of Southampton, Southampton, United Kingdom.
ACR Open Rheumatol. 2021 Sep;3(9):614-621. doi: 10.1002/acr2.11298. Epub 2021 Jul 20.
Our aims were to examine the effects of heeled shoes on incident knee osteoarthritis (OA) and joint pain.
We used longitudinal data from the Chingford 1000 Women Study (Chingford Study), a prospective cohort of women aged 50 years or older. Participants with musculoskeletal disorders and/or a history of knee-related injury/surgery were excluded. Participants were followed for up to 5 years for incident outcomes including 1) radiographic knee OA (RKOA) and 2) joint pain (feet, knees, hips, and back). Footwear data, including ever worn heels of 2 inches or more and daytime/evening hours (per week) spent wearing heeled shoes over five decades (ages <20 years, 20-30 years, 30-40 years, and >50 years), were available at Year 10 whereas knee radiographs and joint symptom data were also collected at Year 15. Cumulative time spent wearing heeled shoes was calculated for women reporting ever-use of heeled shoes (≥2 inches). Multiple logistic regression was used to examine the relationship between exposures and outcomes (from Year 10 to Year 15).
A total of 356 women were eligible at Year 10 with a median (interquartile range) age of 60 (56-65) years. Compared with non-use, ever-use of heeled shoes (≥2 inches) was not associated with incident RKOA (1.35; 95% confidence interval: 0.56-3.27). No associations were observed between increasing cumulative time spent wearing heels and incident outcomes.
Compared with the non-use of heeled shoes, ever-use of heels (≥2 inches) was not associated with incident RKOA and incident joint symptoms. Further, increasing cumulative time spent wearing heels was not associated with any of our outcomes.
我们的目的是研究高跟鞋对膝关节骨性关节炎（OA）发病及关节疼痛的影响。
我们使用了来自钦福德千名女性研究（钦福德研究）的纵向数据，这是一个50岁及以上女性的前瞻性队列研究。排除患有肌肉骨骼疾病和/或有膝关节相关损伤/手术史的参与者。对参与者进行长达5年的随访，观察包括1）膝关节X线骨性关节炎（RKOA）和2）关节疼痛（足部、膝盖、臀部和背部）在内的发病结局。在第10年可获得鞋类数据，包括是否曾穿2英寸或更高的高跟鞋以及在五个十年（年龄<20岁、20 - 30岁、30 - 40岁和>50岁）中每周白天/晚上穿高跟鞋的时长，而在第15年还收集了膝关节X线片和关节症状数据。计算报告曾使用高跟鞋（≥2英寸）的女性穿高跟鞋的累计时长。采用多因素logistic回归分析来研究暴露因素与结局（从第10年到第15年）之间的关系。
在第10年，共有356名女性符合条件，年龄中位数（四分位间距）为60（56 - 65）岁。与未穿高跟鞋相比，曾穿高跟鞋（≥2英寸）与RKOA发病无关（比值比为1.35；95%置信区间：0.56 - 3.27）。未观察到穿高跟鞋累计时长增加与发病结局之间存在关联。
与不穿高跟鞋相比，曾穿高跟鞋（≥2英寸）与RKOA发病及关节症状发病无关。此外，穿高跟鞋累计时长增加与我们所观察的任何结局均无关联。
