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原发性瓣膜的头状葡萄球菌性心内膜炎

Staphylococcus capitis Endocarditis of a Native Valve.

作者信息

Douedi Steven, Odak Mihir, Ravin Andrew, Campbell Natasha

机构信息

Internal Medicine, Jersey Shore University Medical Center, Neptune City, USA.

出版信息

Cureus. 2021 Jun 18;13(6):e15738. doi: 10.7759/cureus.15738. eCollection 2021 Jun.

DOI:10.7759/cureus.15738
PMID:34290924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8289399/
Abstract

Described as primarily an opportunistic pathogen, is primarily found as normal flora of the human skin but has been defined in literature as being a rare cause of infective endocarditis. We present a case of an otherwise healthy 65-year-old male who presented to our institution with symptoms similar to septic emboli. Blood cultures were obtained and ultimately grew in both bottles with repeat cultures one day later confirming the growth. A transthoracic echocardiogram was performed showing an ejection fraction of 60-65% and a thickened mitral value with mild-to-moderate mitral regurgitation. He was ultimately treated with IV cefazolin and improved with symptom resolution in outpatient follow-up. pathogenesis continues to be poorly understood, yet aggressive management with surgery and antibiotics has proven to decrease morbidity and mortality.

摘要

被描述为主要是一种机会性病原体,主要作为人类皮肤的正常菌群被发现,但在文献中被定义为感染性心内膜炎的罕见病因。我们报告一例65岁的健康男性病例,他因出现类似于脓毒性栓子的症状前来我院就诊。采集了血培养样本,最终两个培养瓶中均培养出该病原体,一天后重复培养证实了其生长。进行了经胸超声心动图检查,显示射血分数为60 - 65%,二尖瓣增厚伴轻度至中度二尖瓣反流。他最终接受了静脉注射头孢唑林治疗,并在门诊随访中症状缓解,病情好转。该病原体的发病机制仍知之甚少,但手术和抗生素的积极治疗已被证明可降低发病率和死亡率。 (原文中存在一处未明确的病原体名称,翻译时保留了英文表述。)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b20/8289399/fd1feaf10b0e/cureus-0013-00000015738-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b20/8289399/3edc06819901/cureus-0013-00000015738-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b20/8289399/73ccc8ce4601/cureus-0013-00000015738-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b20/8289399/a8f84d65556a/cureus-0013-00000015738-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b20/8289399/fd1feaf10b0e/cureus-0013-00000015738-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b20/8289399/3edc06819901/cureus-0013-00000015738-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b20/8289399/73ccc8ce4601/cureus-0013-00000015738-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b20/8289399/a8f84d65556a/cureus-0013-00000015738-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b20/8289399/fd1feaf10b0e/cureus-0013-00000015738-i04.jpg

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本文引用的文献

1
Surgical management of Staphylococcus capitis prosthetic valve infective endocarditis: Retrospective review of a 10-year single center experience and review of the literature.头状葡萄球菌人工瓣膜感染性心内膜炎的外科治疗:10 年单中心经验回顾及文献复习。
J Infect Public Health. 2020 Nov;13(11):1705-1709. doi: 10.1016/j.jiph.2020.09.010. Epub 2020 Oct 11.
2
Current AATS guidelines on surgical treatment of infective endocarditis.美国胸外科医师协会(AATS)目前关于感染性心内膜炎外科治疗的指南。
Ann Cardiothorac Surg. 2019 Nov;8(6):630-644. doi: 10.21037/acs.2019.10.05.
3
Native valve Staphylococcus capitis infective endocarditis: a mini review.
头状葡萄球菌感染性心内膜炎:一篇小型综述。
Infection. 2020 Feb;48(1):3-5. doi: 10.1007/s15010-019-01311-8. Epub 2019 May 11.
4
Coagulase-Negative Staphylococcus Skin and Soft Tissue Infections.凝固酶阴性葡萄球菌皮肤及软组织感染。
Am J Clin Dermatol. 2018 Oct;19(5):671-677. doi: 10.1007/s40257-018-0362-9.
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Infective endocarditis.感染性心内膜炎。
Nat Rev Dis Primers. 2016 Sep 1;2:16059. doi: 10.1038/nrdp.2016.59.
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Infective Endocarditis Presenting as Complete Heart Block With an Unexpected Finding of a Cardiac Abscess and Purulent Pericarditis.以完全性心脏传导阻滞为表现的感染性心内膜炎,意外发现心脏脓肿和脓性心包炎。
J Clin Med Res. 2015 Nov;7(11):890-5. doi: 10.14740/jocmr2228w. Epub 2015 Sep 25.
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Insights on virulence from the complete genome of Staphylococcus capitis.来自头状葡萄球菌全基因组的毒力见解。
Front Microbiol. 2015 Sep 23;6:980. doi: 10.3389/fmicb.2015.00980. eCollection 2015.
8
Prosthetic valve endocarditis caused by Staphylococcus capitis: report of 4 cases.头状葡萄球菌引起的人工瓣膜心内膜炎:4例报告
J Cardiothorac Surg. 2011 Oct 7;6:131. doi: 10.1186/1749-8090-6-131.
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Complications of infective endocarditis.感染性心内膜炎的并发症
Cardiovasc Hematol Disord Drug Targets. 2009 Dec;9(4):240-8. doi: 10.2174/1871529x10909040240.