Department of Medicine, Prince Mohammed Bin Abdulaziz Hospital, Ministry of Health, Riyadh, Saudi Arabia.
Infectious Diseases Division, Department of Medicine, Prince Mohamed Bin Abdulaziz Hospital, Ministry of Health, Riyadh, Saudi Arabia.
Infection. 2020 Feb;48(1):3-5. doi: 10.1007/s15010-019-01311-8. Epub 2019 May 11.
Even though prosthetic valve endocarditis due to coagulase-negative staphylococci (CoNS) is widely documented and attracts global attention, native valve endocarditis due to CoNS has been also described lately and may warrant closer attention due to the relative increased incidence.
We describe a 35-year-old male patient who is a former resident of a long-term health-care facility with multiple co-morbidities, diagnosed with native aortic valve S. capitis endocarditis and underwent conservative antimicrobial treatment with full recovery and no recurrence after 6 months' follow-up. In addition, we reviewed the English literature on all reported cases of S. capitis endocarditis.
Infective endocarditis due to S. capitis has thus far been described in 13 patients. All but three had involved native valves with two infected prosthetic valves and a single case of infection in an implanted transvenous pacemaker. Although the number of cases of endocarditis due to S. capitis is small, early removal of either a prosthetic valve or infected pacemaker would appear prudent, while native valve endocarditis could successfully be treated with appropriate antimicrobials alone.
Staphylococcus capitis is classified as coagulase-negative staphylococci with the inherent ability to cause debilitating native valve endocarditis and is usually managed conservatively.
尽管凝固酶阴性葡萄球菌（CoNS）引起的人工瓣膜心内膜炎已有广泛报道，并引起全球关注，但最近也有 CoNS 引起的原发性瓣膜心内膜炎的描述，由于发病率相对增加，可能需要更密切关注。
我们描述了一位 35 岁的男性患者，他曾是长期医疗机构的居民，患有多种合并症，被诊断为原发性主动脉瓣 S. capitis 心内膜炎，并接受了保守的抗菌治疗，完全康复，6 个月随访后无复发。此外，我们回顾了所有报道的 S. capitis 心内膜炎病例的英文文献。
到目前为止，已有 13 例 S. capitis 引起的感染性心内膜炎的报道。除了三例外，其余病例均涉及原发性瓣膜，其中两例感染了人工瓣膜，一例感染了植入式经静脉起搏器。尽管 S. capitis 引起的心内膜炎病例数量较少，但似乎应早期移除人工瓣膜或感染的起搏器，而原发性瓣膜心内膜炎可以单独使用适当的抗菌药物成功治疗。
头状葡萄球菌被归类为凝固酶阴性葡萄球菌，具有引起衰弱的原发性瓣膜心内膜炎的固有能力，通常采用保守治疗。
