Niazi Mashhadi Zahra, Irani Morvarid, Kiyani Mask Mahin, Methie Clara
Student Research Committee, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.
Department of Midwifery, School of Nursing and Midwifery, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.
Avicenna J Phytomed. 2021 Jul-Aug;11(4):324-331. doi: 10.22038/AJP.2021.17813.
During recent years, evidence-based practice as a way to support higher standards of care was emphasized by health care policymakers. Sexual dysfunction (SD) is a common problem that affects the quality of life in individuals. Today, the use of extract (GBE) for treating SD has been considered, so this study was performed to evaluate the current evidence for the efficacy and safety of ginkgo in treating SD.
In this review study, electronic databases of PubMed, Scopus, Cochrane, Google Scholar, Web of science and Persian databases such as SID and Magiran were searched up to March 2020, to identify all the studies reporting the effect of GBE for effectiveness on sexual function and its safety. The search was performed using the keywords of Ginkgo, , Complementary and alternative medicine, women sexual dysfunction, and male sexual dysfunction. The quality of included studies was assessed using the Oxford Center for Evidence Based Medicine checklist.
Among 156 articles found in the initial search, 5 randomized controlled trials (475 participants) were selected for this study. After a meticulous review, we found that can have positive effects on the sexual function of postmenopausal women, while evidence shows that it has no effect on the sexual function of antidepressants users. Headaches and gastrointestinal disturbance were among the adverse events mentioned in several trials.
We concluded that has limited positive effects on sexual function and more studies are needed to confirm these findings.
近年来，循证医学实践作为一种支持更高护理标准的方式，受到了医疗保健政策制定者的重视。性功能障碍（SD）是一个影响个体生活质量的常见问题。如今，银杏提取物（GBE）治疗SD的应用已被纳入考量，因此本研究旨在评估银杏治疗SD有效性和安全性的现有证据。
在这项综述研究中，检索了截至2020年3月的PubMed、Scopus、Cochrane、谷歌学术、科学网等电子数据库以及波斯数据库如SID和Magiran，以识别所有报告GBE对性功能有效性及其安全性影响的研究。检索使用了银杏、补充和替代医学、女性性功能障碍和男性性功能障碍等关键词。纳入研究的质量使用牛津循证医学中心清单进行评估。
在初步检索中找到的156篇文章中，本研究选择了5项随机对照试验（475名参与者）。经过细致审查，我们发现GBE对绝经后女性的性功能可能有积极影响，而证据表明其对使用抗抑郁药者的性功能没有影响。头痛和胃肠道不适是多项试验中提到的不良事件。
我们得出结论，GBE对性功能的积极影响有限，需要更多研究来证实这些发现。
