Division of Hand, Plastic and Aesthetic Surgery, University Hospital, LMU Munich, Munich, Germany.
Department of Plastic, Reconstructive, Hand and Burn Surgery, Bogenhausen Academic Teaching Hospital, Munich, Germany.
J Plast Surg Hand Surg. 2022 Feb;56(1):47-52. doi: 10.1080/2000656X.2021.1914638. Epub 2021 Jul 22.
The physiological differences between genders have significant implications for health and disease. With regard to microsurgery, results remain elusive as to whether male or female gender is an independent risk factor for free flap reconstruction. This study evaluated the impact of gender on outcomes of lower-extremity free-flap reconstructions. Within 7 years, 358 patients received 393 microvascular lower limb free flap reconstructions. The cases were divided into two groups according to patients' gender: male vs. female. Retrospective data analysis evaluated patients' demographics, perioperative details, surgical complications and flap outcomes over a 3-month follow-up period. Major and minor surgical complications, including total and partial flap loss, showed no significant differences between the investigated groups (>.05). In addition, there was no significant difference with regard to the rate of surgical revision surgery, or the incidence of arterial and venous thrombosis (>.05). Comparison of different flap types (fasciocutaneous ALT vs. gracilis muscle flaps) and type of anastomosis (end-to-end vs. end-to-side) also revealed no difference in outcomes in respect to gender. In conclusion, gender cannot be regarded as an independent risk factor for free flap reconstructions in patients with lower-extremity defects.
性别之间的生理差异对健康和疾病有重大影响。就显微外科而言，男性或女性性别是否是游离皮瓣重建的独立危险因素，其结果仍难以捉摸。本研究评估了性别对下肢游离皮瓣重建结果的影响。7 年内，358 例患者接受了 393 例下肢游离血管皮瓣重建。根据患者的性别将病例分为两组：男性与女性。回顾性数据分析评估了患者的人口统计学、围手术期细节、手术并发症以及 3 个月随访期间皮瓣的结果。主要和次要手术并发症，包括总皮瓣和部分皮瓣坏死，在研究组之间没有显著差异（>.05）。此外，手术修正手术的比率以及动静脉血栓形成的发生率也没有显著差异（>.05）。不同皮瓣类型（腓肠浅动脉穿支皮瓣 vs. 股薄肌皮瓣）和吻合类型（端端吻合 vs. 端侧吻合）的比较也表明，性别与皮瓣结果之间没有差异。总之，性别不能被视为下肢缺损患者游离皮瓣重建的独立危险因素。
