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未指定供体活体肾移植后心理健康的正反两方面:一项队列研究。

Positive and negative aspects of mental health after unspecified living kidney donation: A cohort study.

机构信息

Department of Internal Medicine, Erasmus MC Transplant Institute, University Medical Center, Rotterdam, The Netherlands.

Department of Psychiatry, Medical Psychology and Psychotherapy, Erasmus Medical Center, Rotterdam, The Netherlands.

出版信息

Br J Health Psychol. 2022 May;27(2):374-389. doi: 10.1111/bjhp.12549. Epub 2021 Jul 22.

Abstract

OBJECTIVES

Unspecified donors give a kidney to a stranger with end-stage kidney failure. There has been little research on the long-term impact of unspecified donation on mental health outcomes. The aim of this study was to assess the positive and negative aspects of mental health among unspecified donors.

DESIGN

We invited all unspecified donors who donated a kidney between 2000 and 2016 at our centre to participate in an interview and to complete validated questionnaires.

METHODS

We measured positive mental health using the Dutch Mental Health Continuum-Short Form (MHC-SF), psychological complaints using the Symptoms Checklist-90 (SCL-90) and psychiatric diagnoses using the Mini-International Neuropsychiatric Interview (M.I.N.I.) Screen for all donors and the M.I.N.I. Plus on indication.

RESULTS

Of the 134 eligible donors, 114 participated (54% female; median age 66 years), a median of 6 years post-donation. Scores on emotional and social well-being subscales of the MHC-SF were significantly higher than in the general population. Psychological symptoms were comparable to the general population. Thirty-two per cent of donors had a current or lifetime psychiatric diagnosis. Psychological symptoms did not significantly change between the pre-donation screening and the post-donation study.

CONCLUSIONS

We concluded that, with the appropriate screening, unspecified donation is a safe procedure from a psychological perspective.

摘要

目的

未指定的捐赠者将肾脏捐给患有终末期肾衰竭的陌生人。关于未指定捐赠对心理健康结果的长期影响的研究甚少。本研究旨在评估未指定捐赠者心理健康的积极和消极方面。

设计

我们邀请了在我们中心于 2000 年至 2016 年间进行过未指定肾脏捐赠的所有捐赠者参加访谈并完成了经过验证的问卷。

方法

我们使用荷兰心理健康连续体-短表(MHC-SF)来衡量积极的心理健康,使用症状清单-90(SCL-90)来衡量心理困扰,使用迷你国际神经精神访谈(MINI)Screen 对所有捐赠者进行精神科诊断,并根据需要使用 MINI Plus。

结果

在 134 名符合条件的捐赠者中,有 114 名(54%为女性;中位年龄 66 岁)参加了研究,中位随访时间为 6 年。MHC-SF 的情感和社会福祉子量表得分明显高于一般人群。心理症状与一般人群相当。32%的捐赠者有当前或终身精神科诊断。捐赠前筛查和捐赠后研究之间,心理症状并未显著改变。

结论

我们得出结论,经过适当的筛查,从心理角度来看,未指定的捐赠是一种安全的程序。

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