Viszeralmedizinisches Zentrum, Department of Medicine, Evangelisches Diakoniekrankenhaus Freiburg. Academic Teaching Hospital, University of Freiburg, Freiburg i.Br., Germany.
Gastroenterologie, Asklepios Klinik Altona, Hamburg, Germany.
Z Gastroenterol. 2021 Nov;59(11):1197-1204. doi: 10.1055/a-1495-6352. Epub 2021 Jul 23.
The complete occlusion of bilioenteric anastomoses is a rare and challenging clinical condition. Repeated surgery is burdened with technical difficulties and significant morbidity. We report the first series of completely occluded bilioenteric anastomoses resp. distal bile duct successfully treated by simultaneous percutaneous and retrograde endoscopic interventions.
This case series includes 4 patients with obstructive jaundice and/or recurring cholangitis and pain due to complete fibrotic occlusion of a hepaticojejunostomy (3 patients) and the distal bile duct (1 patient). After performing PTCD and stepwise dilation of the biliocutaneous tract, we tried to approach the occluded anastomosis from 2 sides by simultaneous percutaneous cholangioscopy and peroral device-assisted enteroscopy/duodenoscopy. By cutting through the separating tissue layer with a needle knife under endoscopic and fluoroscopic control using diaphanoscopy, a new anastomosis should be established followed by dilation of the neoanastomosis with subsequent percutaneous transhepatic drainage for a minimum of 1 year to prevent re-occlusion.
The Rendez-vous maneuver was successful in 3/4 cases. In one case, the retrograde access to the anastomosis failed, so the neoanastomosis was cut under cholangioscopic and fluoroscopic guidance only. The neoanastomosis could be established successfully in all 4 cases. Jaundice, cholangitis, and pain disappeared. Minor periinterventional adverse events were cholangitis (n = 1) and pneumonia (n = 1) due to aspiration, which could be managed conservatively. No serious adverse events were observed, and no re-occlusion of any neoanastomosis occurred during the follow-up before and after removal of the percutaneous drainage.
Simultaneous percutaneous cholangioscopy and device-assisted enteroscopy/duodenoscopy with endoscopic creation of a neoanastomosis is a possible concept for the treatment of completely occluded bilioenteric anastomoses and distal bile ducts. This case series confirms the feasibility, safety, and long-term effectiveness of this treatment.
胆肠吻合口完全闭塞是一种罕见且具有挑战性的临床情况。反复手术存在技术难度大、并发症发生率高的问题。我们报告首例完全闭塞的胆肠吻合口和(或)远端胆管通过经皮和逆行内镜联合介入治疗成功治愈的系列病例。
该病例系列包括 4 例因胆肠吻合口(3 例)和(或)远端胆管(1 例)纤维性完全闭塞而出现梗阻性黄疸和/或反复发作性胆管炎和疼痛的患者。在实施经皮肝穿刺胆道引流(PTCD)和逐步扩张胆肠吻合口后,我们尝试通过经皮逆行胆胰管镜检查和经口设备辅助的内镜/十二指肠镜检查从 2 个方向接近闭塞的吻合口。在透视和内镜控制下,用针刀切开分隔组织层,建立新的吻合口,然后用经皮经肝胆道引流(PTBD)扩张新吻合口,持续至少 1 年以防止再闭塞。
在 4 例患者中,Rendez-vous 操作成功 3 例。1 例逆行进入吻合口失败,因此仅在胆胰管镜和透视引导下切开吻合口。4 例患者均成功建立新吻合口。黄疸、胆管炎和疼痛消失。围手术期出现轻微并发症,1 例为胆管炎,1 例为吸入性肺炎,均经保守治疗。未观察到严重不良事件,在拔除经皮引流管前后的随访期间,没有新吻合口再闭塞。
经皮逆行胆胰管镜检查和设备辅助的内镜/十二指肠镜检查联合内镜下建立新吻合口可能是治疗完全闭塞的胆肠吻合口和远端胆管的一种方法。该病例系列证实了该治疗方法的可行性、安全性和长期疗效。