Hibino Hidetaka, Gorniak Stacey L
Department of Health and Human Performance, University of Houston, 3855 Holman St., Garrison 104, Houston, TX, 77204-6015, USA.
Heart Fail Rev. 2022 Jul;27(4):1043-1051. doi: 10.1007/s10741-021-10145-2. Epub 2021 Jul 24.
While patients with heart failure experience a wide range of symptoms, evidence is mounting that patients with heart failure suffer from reduced functional independence. Given that the number of patients with heart failure is rising and considering the adverse outcomes of reduced functional independence, understanding the underlying mechanisms of reduced functionality in patients with heart failure is of increasing importance. Yet, little information exists on how heart failure negatively affects functional independence, including motor function. This article summarizes reports of reduced independence and highlights its significant adverse outcomes in the patients with heart failure. Finally, this article discusses potential causes of reduced independence based on existing reports of impaired central and peripheral nervous systems in the patients with heart failure. Overall, the article provides a solid foundation for future studies investigating motor impairments in patients with heart failure. Such studies may lead to advances in treatment and prevention of reduced independence associated with heart failure, which ultimately contribute to the well-being of patients with heart failure.
虽然心力衰竭患者会经历各种各样的症状，但越来越多的证据表明，心力衰竭患者的功能独立性下降。鉴于心力衰竭患者的数量在不断增加，并且考虑到功能独立性下降的不良后果，了解心力衰竭患者功能下降的潜在机制变得越来越重要。然而，关于心力衰竭如何对功能独立性产生负面影响，包括对运动功能的影响，目前知之甚少。本文总结了关于独立性下降的报告，并强调了其在心力衰竭患者中的重大不良后果。最后，本文根据现有关于心力衰竭患者中枢和外周神经系统受损的报告，讨论了独立性下降的潜在原因。总体而言，本文为未来研究心力衰竭患者的运动障碍提供了坚实的基础。此类研究可能会推动与心力衰竭相关的独立性下降的治疗和预防取得进展，最终有助于心力衰竭患者的福祉。
