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Cognitive impairment and medication adherence in outpatients with heart failure.心力衰竭门诊患者的认知障碍与药物依从性。
Heart Lung. 2012 Nov-Dec;41(6):572-82. doi: 10.1016/j.hrtlng.2012.06.001. Epub 2012 Jul 10.
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Impairment of activities of daily living and incident heart failure in community-dwelling older adults.日常生活活动能力受损与社区居住的老年人心力衰竭事件。
Eur J Heart Fail. 2012 Jun;14(6):581-7. doi: 10.1093/eurjhf/hfs034. Epub 2012 Apr 4.
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Heart disease and stroke statistics--2012 update: a report from the American Heart Association.《2012年心脏病和中风统计数据更新:美国心脏协会报告》
Circulation. 2012 Jan 3;125(1):e2-e220. doi: 10.1161/CIR.0b013e31823ac046. Epub 2011 Dec 15.
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Impact of medication nonadherence on hospitalizations and mortality in heart failure.药物治疗不依从对心力衰竭患者住院和死亡的影响。
J Card Fail. 2011 Aug;17(8):664-9. doi: 10.1016/j.cardfail.2011.04.011. Epub 2011 Jun 23.
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Executive dysfunction and depressive symptoms associated with reduced participation of people with severe congestive heart failure.执行功能障碍和抑郁症状与严重充血性心力衰竭患者参与度降低有关。
Am J Occup Ther. 2011 May-Jun;65(3):306-13. doi: 10.5014/ajot.2011.000588.
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Brain axonal and myelin evaluation in heart failure.心力衰竭患者的脑轴突和髓鞘评估。
J Neurol Sci. 2011 Aug 15;307(1-2):106-13. doi: 10.1016/j.jns.2011.04.028. Epub 2011 May 25.
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Executive function and instrumental activities of daily living in mild cognitive impairment and Alzheimer's disease.执行功能和日常生活活动在轻度认知障碍和阿尔茨海默病中的作用。
Alzheimers Dement. 2011 May;7(3):300-8. doi: 10.1016/j.jalz.2010.04.005.
8
Cognitive impairment is independently associated with reduced instrumental activities of daily living in persons with heart failure.认知障碍与心力衰竭患者日常生活活动能力下降独立相关。
J Cardiovasc Nurs. 2012 Jan-Feb;27(1):44-50. doi: 10.1097/JCN.0b013e318216a6cd.
9
A brief neuropsychological battery for use in the chronic heart failure population.用于慢性心力衰竭人群的简短神经心理学成套测验。
Eur J Cardiovasc Nurs. 2012 Jun;11(2):223-30. doi: 10.1016/j.ejcnurse.2011.03.007. Epub 2012 Mar 6.
10
Predictors of modifications in instrumental activities of daily living in persons with heart failure.预测心力衰竭患者日常生活活动能力改变的因素。
J Cardiovasc Nurs. 2011 Mar-Apr;26(2):89-98. doi: 10.1097/JCN.0b013e3181ec1352.

执行功能障碍与心力衰竭患者功能独立性降低独立相关。

Executive dysfunction is independently associated with reduced functional independence in heart failure.

作者信息

Alosco Michael L, Spitznagel Mary Beth, Raz Naftali, Cohen Ronald, Sweet Lawrence H, Colbert Lisa H, Josephson Richard, van Dulmen Manfred, Hughes Joel, Rosneck Jim, Gunstad John

机构信息

Department of Psychology, Kent State University, Kent, OH, USA.

出版信息

J Clin Nurs. 2014 Mar;23(5-6):829-36. doi: 10.1111/jocn.12214. Epub 2013 May 8.

DOI:10.1111/jocn.12214
PMID:23650879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5022367/
Abstract

AIMS AND OBJECTIVES

To examine the independent association between executive function with instrumental activities of daily living and health behaviours in older adults with heart failure.

BACKGROUND

Executive function is an important contributor to functional independence as it consists of cognitive processes needed for decision-making, planning, organising and behavioural monitoring. Impairment in this domain is common in heart failure patients and associated with reduced performance of instrumental activities of daily living in many medical and neurological populations. However, the contribution of executive functions to functional independence and healthy lifestyle choices in heart failure patients has not been fully examined.

DESIGN

Cross-sectional analyses.

METHODS

One hundred and seventy-five heart failure patients completed a neuropsychological battery and echocardiogram. Participants also completed the Lawton-Brody Instrumental Activities of Daily Living Scale and reported current cigarette use.

RESULTS

Hierarchical regressions revealed that reduced executive function was independently associated with worse instrumental activity of daily living performance with a specific association for decreased ability to manage medications. Partial correlations showed that executive dysfunction was associated with current cigarette use.

CONCLUSIONS

Our findings suggest that executive dysfunction is associated with poorer functional independence and contributes to unhealthy behaviours in heart failure. Future studies should examine whether heart failure patients benefit from formal organisation schema (i.e. pill organisers) to maintain independence.

RELEVANCE TO CLINICAL PRACTICE

Screening of executive function in heart failure patients may provide key insight into their ability to perform daily tasks, including the management of treatment recommendations.

摘要

目的

探讨心力衰竭老年患者执行功能与日常生活工具性活动及健康行为之间的独立关联。

背景

执行功能是功能独立性的重要因素,因为它由决策、规划、组织和行为监测所需的认知过程组成。这一领域的损害在心力衰竭患者中很常见,并且在许多医学和神经学人群中与日常生活工具性活动表现降低有关。然而,执行功能对心力衰竭患者功能独立性和健康生活方式选择的贡献尚未得到充分研究。

设计

横断面分析。

方法

175名心力衰竭患者完成了一套神经心理学测试和超声心动图检查。参与者还完成了洛顿-布罗迪日常生活工具性活动量表,并报告了当前的吸烟情况。

结果

分层回归显示,执行功能降低与日常生活工具性活动表现较差独立相关,尤其是在药物管理能力下降方面存在特定关联。偏相关性分析表明,执行功能障碍与当前吸烟情况有关。

结论

我们的研究结果表明,执行功能障碍与功能独立性较差相关,并导致心力衰竭患者出现不健康行为。未来的研究应探讨心力衰竭患者是否能从正式的组织方案(如药盒)中受益以维持独立性。

与临床实践的相关性

对心力衰竭患者进行执行功能筛查可能有助于深入了解他们执行日常任务的能力,包括治疗建议的管理。