Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
Trends Mol Med. 2021 Oct;27(10):928-930. doi: 10.1016/j.molmed.2021.07.007. Epub 2021 Jul 22.
Sutherland et al. recently reported the in vitro inhibition of Helicobacter hepaticus cytochrome c (cyt c) synthase, which may inactivate c-type cytochromes in this and in other pathogenic bacteria. Here, I discuss the impact of this work, which identifies this conserved synthase as a potential antibacterial target.
Sutherland 等人最近报道了对肝螺杆菌细胞色素 c（cyt c）合酶的体外抑制作用，这可能会使该菌和其他病原菌中的 c 型细胞色素失活。在此，我将讨论这项工作的影响，该工作确定了这种保守的合酶作为一种潜在的抗菌靶标。
