儿童骨髓增殖性肿瘤。

Pediatric Myeloproliferative Neoplasms.

机构信息

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

出版信息

Clin Lab Med. 2021 Sep;41(3):529-540. doi: 10.1016/j.cll.2021.04.010.

DOI:10.1016/j.cll.2021.04.010

PMID:34304780

Abstract

Myeloproliferative neoplasms can present early in life and may present a diagnostic challenge. Very few studies have focused on the diagnosis, prognosis, and therapy for pediatric myeloproliferative neoplasms. This article focuses on chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis in children.

摘要

骨髓增殖性肿瘤可在生命早期出现，且可能构成诊断挑战。仅有少数研究聚焦于儿科骨髓增殖性肿瘤的诊断、预后和治疗。本文重点介绍儿童慢性髓性白血病、特发性血小板增多症、真性红细胞增多症和原发性骨髓纤维化。