Macavei I, Galatâr N
Morphol Embryol (Bucur). 1989 Apr-Jun;35(2):117-27.
The myeloproliferative disorders (MPD) are a domain in which the bone marrow biopsy (BMB) greatly proved its utility. We have studied the histology of the bone marrow (BM) in all the four entities of MPD: chronic myeloid leukemia (CML) with its subtype, chronic megakaryocytic granulocytic myelosis (CMGM), polycythemia vera (PV), hemorrhagic thrombocythemia (HT) and myeloid metaplasia with myelofibrosis (MMM). The work presents in short some of the clinical and hematologic characters of MPD with special stress upon the histologic modifications of BM, either specific or common to all MPD entities, underlying also the criteria for differential diagnosis.
骨髓增殖性疾病（MPD）是骨髓活检（BMB）充分证明其效用的一个领域。我们研究了MPD所有四个类型的骨髓（BM）组织学：慢性粒细胞白血病（CML）及其亚型慢性巨核细胞粒细胞性骨髓增生症（CMGM）、真性红细胞增多症（PV）、出血性血小板增多症（HT）以及伴有骨髓纤维化的髓样化生（MMM）。这项工作简要介绍了MPD的一些临床和血液学特征，特别强调了BM的组织学改变，这些改变对于所有MPD类型来说，要么具有特异性，要么具有共性，同时也阐述了鉴别诊断的标准。
