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胸膜孤立性纤维瘤的不良生物学因素及处理的意义

Implications of Adverse Biological Factors and Management of Solitary Fibrous Tumors of the Pleura.

作者信息

Andrews Weston G, Vallières Eric

机构信息

Swedish Cancer Institute, 1101 Madison Street, Suite 900, Seattle, WA 98104, USA.

Division of Thoracic Surgery, Swedish Cancer Institute, 1101 Madison Street, Suite 900, Seattle, WA 98104, USA.

出版信息

Thorac Surg Clin. 2021 Aug;31(3):347-355. doi: 10.1016/j.thorsurg.2021.04.009. Epub 2021 Jun 9.

DOI:10.1016/j.thorsurg.2021.04.009
PMID:34304844
Abstract

Solitary fibrous tumors arise in many locations throughout the body and are genetically and histologically considered a single disease. Solitary fibrous tumors of the pleura (SFTP) are the most common tumor of this disease. Most of the SFTPs are treated with surgery alone, and chemotherapy and radiotherapy do not seem to play a role in treatment. Tumor size and unfavorable histology are risk factors for malignant potential. Incomplete resection is an important risk factor for recurrence.

摘要

孤立性纤维性肿瘤可发生于全身多个部位,在遗传学和组织学上被视为单一疾病。胸膜孤立性纤维性肿瘤(SFTP)是该疾病最常见的肿瘤类型。大多数SFTP仅通过手术治疗,化疗和放疗似乎在治疗中不起作用。肿瘤大小和不良组织学是恶性潜能的危险因素。切除不完全是复发的重要危险因素。

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