School of Medical Sciences, University of Campinas, Campinas, SP, 13083-887, Brazil.
Department of Kinesiology, University of Wisconsin-Eau Claire, Eau Claire, WI, 54702, USA.
Disabil Health J. 2022 Jan;15(1):101173. doi: 10.1016/j.dhjo.2021.101173. Epub 2021 Jul 21.
Sleep quality is associated with physical functioning in adults, but this has not been examined in those with Down syndrome (DS). High body mass index (BMI) and accelerated aging, both common in adults with DS, may alter the relationship between sleep quality and physical functioning in this population.
To examine sleep quality indicators and its association with physical functioning in adults with DS, and whether associations are altered by BMI and age.
Participants were 15 adults with DS (8 women; age 29 ± 14 years). We evaluated sleep quality over seven days with wrist-worn accelerometers and physical functioning with the timed-up-and-go (TUG) and 6-min walk (6 MW) tests. We examined the associations between sleep quality and physical functioning variables using Spearman's rho.
Sleep quality indicators were: total sleep time 407 ± 54 min; latency 26.8 ± 21 min; efficiency 73.9 ± 12 %; wake after sleep onset 122.8 ± 65.2 min; number of awakenings 21.0 ± 6.2; and average length of awakenings 6.1 ± 3 min. Total sleep time and average length of awakenings were significantly associated with 6 MW distances (rho = 0.58 and -0.69; p < 0.05, respectively). After controlling for age and BMI, 6 MW distance was significantly associated with total sleep time, latency, efficiency, and average length of awakenings (rho = 0.56, -0.73, 0.60, and -0.87; p < 0.05, respectively). TUG was significantly associated with total time in bed (rho = 0.71); p < 0.05).
Sleep quality indicators are associated with walking performance in adults with DS. Age and BMI strengthen the relationship between sleep quality and physical functioning.
睡眠质量与成年人的身体机能有关，但这一点尚未在唐氏综合征（DS）患者中得到验证。在 DS 患者中，常见的高体重指数（BMI）和加速衰老可能会改变这一人群中睡眠质量与身体机能之间的关系。
研究 DS 成人的睡眠质量指标及其与身体机能的关系，以及 BMI 和年龄是否会改变这些关系。
参与者为 15 名 DS 成人（8 名女性；年龄 29 ± 14 岁）。我们使用腕戴式加速计在七天内评估睡眠质量，并用计时起立行走（TUG）和 6 分钟步行（6MW）测试评估身体机能。我们使用 Spearman's rho 检验睡眠质量指标与身体机能变量之间的相关性。
睡眠质量指标包括：总睡眠时间 407 ± 54 分钟；潜伏期 26.8 ± 21 分钟；效率 73.9 ± 12%；睡眠后觉醒时间 122.8 ± 65.2 分钟；觉醒次数 21.0 ± 6.2 次；和平均觉醒时间 6.1 ± 3 分钟。总睡眠时间和平均觉醒时间与 6MW 距离显著相关（rho 值分别为 0.58 和-0.69；p<0.05）。在控制年龄和 BMI 后，6MW 距离与总睡眠时间、潜伏期、效率和平均觉醒时间显著相关（rho 值分别为 0.56、-0.73、0.60 和-0.87；p<0.05）。TUG 与总卧床时间显著相关（rho 值为 0.71；p<0.05）。
睡眠质量指标与 DS 成人的步行表现相关。年龄和 BMI 增强了睡眠质量与身体机能之间的关系。
