Tsangaris Adamantios, Alexy Tamas, Kalra Rajat, Kosmopoulos Marinos, Elliott Andrea, Bartos Jason A, Yannopoulos Demetris
Division of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN, United States.
Center for Resuscitation Medicine, University of Minnesota School of Medicine, Minneapolis, MN, United States.
Front Cardiovasc Med. 2021 Jul 7;8:686558. doi: 10.3389/fcvm.2021.686558. eCollection 2021.
Cardiogenic shock accounts for ~100,000 annual hospital admissions in the United States. Despite improvements in medical management strategies, in-hospital mortality remains unacceptably high. Multiple mechanical circulatory support devices have been developed with the aim to provide hemodynamic support and to improve outcomes in this population. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is the most advanced temporary life support system that is unique in that it provides immediate and complete hemodynamic support as well as concomitant gas exchange. In this review, we discuss the fundamental concepts and hemodynamic aspects of VA-ECMO support in patients with cardiogenic shock of various etiologies. In addition, we review the common indications, contraindications and complications associated with VA-ECMO use.
在美国,心源性休克每年导致约10万例住院病例。尽管医疗管理策略有所改进,但院内死亡率仍然高得令人无法接受。人们已开发出多种机械循环支持设备,旨在为这一人群提供血流动力学支持并改善治疗结果。静脉-动脉体外膜肺氧合(VA-ECMO)是最先进的临时生命支持系统,其独特之处在于它能提供即时且完全的血流动力学支持以及同步的气体交换。在本综述中,我们讨论了各种病因的心源性休克患者使用VA-ECMO支持的基本概念和血流动力学方面。此外,我们还综述了与使用VA-ECMO相关的常见适应证、禁忌证和并发症。