Lawson C, Crothers H, Remsing S, Squire I, Zaccardi F, Davies M, Bernhardt L, Reeves K, Lilford R, Khunti K
Department of Cardiovascular Sciences, University of Leicester, and NIHR Cardiovascular Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Real World Evidence Unit, University of Leicester, UK.
EClinicalMedicine. 2021 Jul 14;38:101008. doi: 10.1016/j.eclinm.2021.101008. eCollection 2021 Aug.
Reducing the high patient and economic burden of early readmissions after hospitalisation for heart failure (HF) has become a health policy priority of recent years.
An observational study linking Hospital Episode Statistics to socioeconomic and death data in England (2002-2018). All first hospitalisations with a primary discharge code for HF were identified. Quasi-poisson models were used to investigate trends in 30-day readmissions by age, sex, socioeconomic status and ethnicity.
There were 698,983 HF admissions, median age 81 years [IQR 14].In-hospital deaths reduced by 0.7% per annum (pa), whilst additional deaths at 30-days remained stable at 5%. Age adjusted 30-day readmissions (21% overall), increased by 1.4% pa (95% CI 1.3-1.5). Readmissions for HF (6%) and 'other cardiovascular disease (CVD)' (3%) remained stable, but readmissions for non-CVD causes (12%) increased at a rate of 2.6% (2.4-2.7) pa. Proportions were similar by sex but trends diverged by ethnicity. Black groups experienced an increase in readmissions for HF (1.8% pa, interaction-p 0.03) and South Asian groups had more rapidly increasing readmission rates for non-CVD causes (interaction-p 0.04). Non-CVD readmissions were also more prominent in the least (15%; 15-15) compared to the most affluent group (12%; 12-12). Strongest predictors for HF readmission were Black ethnicity and chronic kidney disease, whilst cardiac procedures were protective. For non-CVD readmissions, strongest predictors were non-CVD comorbidities, whilst cardiologist care was protective.
In HF, despite readmission reduction policies, 30-day readmissions have increased, impacting the least affluent and ethnic minority groups the most.
NIHR.
减轻心力衰竭(HF)住院后早期再入院带来的高昂患者负担和经济负担已成为近年来卫生政策的重点。
一项将医院事件统计数据与英格兰的社会经济和死亡数据相联系的观察性研究(2002 - 2018年)。确定所有以HF为主要出院诊断代码的首次住院病例。使用拟泊松模型按年龄、性别、社会经济地位和种族调查30天再入院率的趋势。
共有698,983例HF住院病例,中位年龄81岁[四分位间距14]。住院死亡率每年降低0.7%,而30天额外死亡率保持稳定在5%。年龄调整后的30天再入院率(总体为21%)每年增加1.4%(95%置信区间1.3 - 1.5)。HF再入院率(6%)和“其他心血管疾病(CVD)”再入院率(3%)保持稳定,但非CVD病因的再入院率(12%)以每年2.6%(2.4 - 2.7)的速度增加。性别间比例相似,但种族间趋势不同。黑人组HF再入院率增加(每年1.8%,交互作用p = 0.03),南亚组非CVD病因的再入院率增长更快(交互作用p = 0.04)。与最富裕组(12%;12 - 12)相比,最贫困组非CVD再入院率也更高(15%;15 - 15)。HF再入院的最强预测因素是黑人种族和慢性肾病,而心脏手术有保护作用。对于非CVD再入院,最强预测因素是非CVD合并症,而心脏病专家护理有保护作用。
在HF方面,尽管有减少再入院的政策,但30天再入院率仍有所上升,对最贫困和少数族裔群体影响最大。
英国国家卫生研究院。