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骨盆骨折患者下肢围手术期深静脉血栓形成:病例对照研究。

The Perioperative Deep Vein Thrombosis in Lower Extremities in Patients With Pelvic Fracture: A Case-Control Study.

机构信息

Department of Orthopedic Trauma, Honghui Hospital, 12480Xi'an Jiaotong University, Xi'an, Shaanxi Province, People's Republic of China.

出版信息

Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211033024. doi: 10.1177/10760296211033024.

Abstract

This study was to investigate the incidences of DVT in lower extremities after pelvic fracture before and after operation, and explore the risk factors. The records of patients with pelvic fractures receiving operation were collected. The patients were examined by preoperative and postoperative ultrasonography, and divided into thrombosis group and non-thrombosis group according to the preoperative and postoperative ultrasonographic results. Totally, 128 patients with pelvic fractures were included in this study. The incidence of DVT was 21.09% preoperatively, and increased to 35.16% postoperatively. Peripheral DVT constituted 92.60% and 86.67% of preoperative and postoperative DVTs, respectively. The results showed that age (odds ratio [OR] = 1.07; 95% CI: 1.01-1.12; = 0.013), fracture classification (OR = 3.80; 95% CI: 1.31-11.00; = 0.014) and D-dimer at admission (OR = 1.04; 95% CI: 1.00-1.08; = 0.029) were independent risk factors of preoperative DVT, and female (OR = 0.21; 95% CI: 0.06-0.81; = 0.023) was independent protective factor. In addition, age (OR, 1.06; 95% CI, 1.00-1.11; = 0.026), operative blood transfusion (OR, 1.34; 95% CI, 1.05-1.72; = 0.020) were independent risk factors of postoperative DVT. In conclusion, the DVT prevention strategy has not changed the high incidence of DVT in pelvic fractures, and orthopedic surgeons should pay more attention to perioperative DVT. When a male or patient with Tile-C type pelvic fracture is at admission, it is should be reminded that the screening the DVT in lower extremities. In addition, the surgeon should stanch bleeding completely, to reduce the blood transfusion and formation of DVT.

摘要

本研究旨在探讨骨盆骨折患者术前和术后下肢深静脉血栓(DVT)的发生率,并探讨其危险因素。收集了接受手术治疗的骨盆骨折患者的病历资料。对患者进行术前和术后超声检查,并根据术前和术后超声检查结果将患者分为血栓组和非血栓组。共纳入 128 例骨盆骨折患者。术前 DVT 发生率为 21.09%,术后上升至 35.16%。术前和术后 DVT 中分别有 92.60%和 86.67%为外周型 DVT。结果显示,年龄(比值比 [OR] = 1.07;95%可信区间:1.01-1.12; = 0.013)、骨折分型(OR = 3.80;95%可信区间:1.31-11.00; = 0.014)和入院时 D-二聚体(OR = 1.04;95%可信区间:1.00-1.08; = 0.029)是术前 DVT 的独立危险因素,而女性(OR = 0.21;95%可信区间:0.06-0.81; = 0.023)是独立的保护因素。此外,年龄(OR,1.06;95%可信区间,1.00-1.11; = 0.026)、手术输血(OR,1.34;95%可信区间,1.05-1.72; = 0.020)是术后 DVT 的独立危险因素。总之,DVT 预防策略并未改变骨盆骨折患者 DVT 发生率高的现状,骨科医生应更加重视围手术期 DVT。当男性或 Tile-C 型骨盆骨折患者入院时,应提醒其筛查下肢 DVT。此外,外科医生应彻底止血,减少输血和 DVT 的形成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35ff/8317243/9029bdd38aeb/10.1177_10760296211033024-fig1.jpg

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