Suppr超能文献

双侧下肢骨折后深静脉血栓形成:463 例回顾性研究。

Deep vein thrombosis in bilateral lower extremities after hip fracture: a retrospective study of 463 patients.

机构信息

Department of Orthopedic Trauma, Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Beilin District, Xi'an, Shaanxi, China.

出版信息

Clin Interv Aging. 2018 Apr 18;13:681-689. doi: 10.2147/CIA.S161191. eCollection 2018.

Abstract

OBJECTIVE

To investigate the incidences of deep vein thrombosis (DVT) before and after operation in inpatients with hip fractures in both lower extremities.

PATIENTS AND METHODS

We collected the clinical data of 463 patients with lower extremities fractures who presented at Xi'an Honghui Hospital between July 1, 2014, and October 31, 2016 and met all the inclusion criteria. Doppler ultrasonography was used to diagnose DVT. The patients were examined preoperatively and postoperatively and divided into the thrombosis and non-thrombosis group according to the ultrasonographic findings. We divided the DVT cases into central, peripheral, and mixed thromboses.

RESULTS

The incidence of preoperative DVT was 34.98%, and the prevalence of DVT on the uninjured side was 13.60%. This composition ratio increased to 57.23% postoperatively, and the prevalence of DVT on the uninjured side was 25.05%. Age (odds ratio [OR], 1.03; 95% CI: 1.01-1.04; =0.002), venous thrombosis at admission (OR, 4.05; 95% CI, 2.30-7.13; =0.000), and the days between the fracture and the operation (OR, 1.10; 95% CI, 1.02-1.20; =0.020) were the independent risk factors of preoperative DVT. Coronary heart disease (OR, 1.85; 95% CI: 1.18-2.89; =0.007), venous thrombosis at admission (OR, 22.35; 95% CI: 6.78-73.60; =0.000), days between fracture and operation (OR, 1.06; 95% CI: 1.01-1.11; =0.021), and blood loss (OR, 1.002; 95% CI: 1.000-1.003; =0.014) were independent risk factors of postoperative DVT.

CONCLUSION

The actual incidence of DVT after hip fracture may be underestimated. The incidences of preoperative and postoperative DVTs and the incidence of DVT on the uninjured limb were high.

摘要

目的

调查双侧下肢髋部骨折住院患者手术前后深静脉血栓(DVT)的发生率。

患者与方法

我们收集了 2014 年 7 月 1 日至 2016 年 10 月 31 日期间在西安红会医院就诊且符合所有纳入标准的 463 例下肢骨折患者的临床资料。采用多普勒超声诊断 DVT。患者术前及术后接受检查,并根据超声检查结果分为血栓组和非血栓组。我们将 DVT 病例分为中央型、外周型和混合型。

结果

术前 DVT 发生率为 34.98%,健侧 DVT 发生率为 13.60%。这一比例在术后增加至 57.23%,健侧 DVT 发生率为 25.05%。年龄(比值比 [OR],1.03;95%可信区间:1.01-1.04;=0.002)、入院时静脉血栓(OR,4.05;95%可信区间,2.30-7.13;=0.000)和骨折至手术的时间(OR,1.10;95%可信区间,1.02-1.20;=0.020)是术前 DVT 的独立危险因素。冠心病(OR,1.85;95%可信区间:1.18-2.89;=0.007)、入院时静脉血栓(OR,22.35;95%可信区间:6.78-73.60;=0.000)、骨折至手术的时间(OR,1.06;95%可信区间,1.01-1.11;=0.021)和出血量(OR,1.002;95%可信区间,1.000-1.003;=0.014)是术后 DVT 的独立危险因素。

结论

髋部骨折后 DVT 的实际发生率可能被低估。术前、术后 DVT 发生率及健侧肢体 DVT 发生率均较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef3f/5912380/8997bde15d42/cia-13-681Fig1.jpg

相似文献

1
Deep vein thrombosis in bilateral lower extremities after hip fracture: a retrospective study of 463 patients.
Clin Interv Aging. 2018 Apr 18;13:681-689. doi: 10.2147/CIA.S161191. eCollection 2018.
2
Deep Vein Thrombosis in the Uninjured Lower Extremity: A Retrospective Study of 1454 Patients With Lower Extremity Fractures.
Clin Appl Thromb Hemost. 2021 Jan-Dec;27:1076029620986862. doi: 10.1177/1076029620986862.
3
Deep vein thrombosis in the lower extremities after femoral neck fracture: A retrospective observational study.
J Orthop Surg (Hong Kong). 2020 Jan-Apr;28(1):2309499019901172. doi: 10.1177/2309499019901172.
4
Correlation Between the Fracture Line Plane and Perioperative Deep Vein Thrombosis in Patients with Tibial Fracture.
Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211067258. doi: 10.1177/10760296211067258.
5
The Perioperative Deep Vein Thrombosis in Lower Extremities in Patients With Pelvic Fracture: A Case-Control Study.
Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211033024. doi: 10.1177/10760296211033024.
6
Deep Vein Thrombosis in Patients with Intertrochanteric Fracture: A Retrospective Study.
Indian J Orthop. 2020 Jul 11;54(Suppl 1):101-108. doi: 10.1007/s43465-020-00166-8. eCollection 2020 Sep.
7
Perioperative incidence and locations of deep vein thrombosis following specific isolated lower extremity fractures.
Injury. 2018 Jul;49(7):1353-1357. doi: 10.1016/j.injury.2018.05.018. Epub 2018 May 22.
9
Analysis of perioperative risk factors for deep vein thrombosis in patients with femoral and pelvic fractures.
J Orthop Surg Res. 2020 Dec 10;15(1):597. doi: 10.1186/s13018-020-02131-5.

引用本文的文献

1
[Preoperative Incidence of Deep Venous Thrombosis and Its Risk Factors in Older Patients with Hip Fracture].
Acta Chir Orthop Traumatol Cech. 2025 Jun;92(2):92-97. doi: 10.55095/achot2024/062.
6
Risk factor analysis and nomogram model of DVT in hip fracture patients at hospital admission.
BMC Musculoskelet Disord. 2025 Feb 25;26(1):189. doi: 10.1186/s12891-025-08308-5.
9
[Risk factors of perioperative deep venous thrombosis of lower extremities in elderly patients with femoral neck fracture].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2024 Nov 15;38(11):1336-1339. doi: 10.7507/1002-1892.202403072.
10
Bibliometric and visualized analysis on hip fracture surgery and venous thromboembolism.
Heliyon. 2024 Aug 13;10(16):e36222. doi: 10.1016/j.heliyon.2024.e36222. eCollection 2024 Aug 30.

本文引用的文献

2
The rate of deep vein thrombosis doubles in trauma patients with hypercoagulable thromboelastography.
J Trauma Acute Care Surg. 2017 Sep;83(3):413-419. doi: 10.1097/TA.0000000000001618.
3
Monitoring of Hypercoagulability by Thromboelastography in Bariatric Surgery.
Med Sci Monit. 2017 Apr 15;23:1819-1826. doi: 10.12659/msm.900769.
6
Deep vein thrombosis and pulmonary embolism.
Lancet. 2016 Dec 17;388(10063):3060-3073. doi: 10.1016/S0140-6736(16)30514-1. Epub 2016 Jun 30.
7
Risk factors for venous thromboembolism after acute trauma: A population-based case-cohort study.
Thromb Res. 2016 Aug;144:40-5. doi: 10.1016/j.thromres.2016.03.026. Epub 2016 Mar 29.
9
Incidence and Factors Predicting Venous Thromboembolism After Surgical Treatment of Fractures Below the Hip.
J Orthop Trauma. 2015 Oct;29(10):e349-54. doi: 10.1097/BOT.0000000000000336.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验