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经皮椎体成形术治疗老年骨质疏松性脊柱骨折的效果及术后下肢深静脉血栓形成的危险因素

Effect of percutaneous vertebroplasty on the treatment of osteoporotic spinal fractures in elderly patients and risk factors for postoperative lower extremity deep vein thrombosis.

作者信息

Chen Jinpeng, Wu Gaochen, Miao Yiqi, Wang Lulu, Meng Fanjian

机构信息

Department of Orthopaedics, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine No. 39 Xiashatang Road, Mudu Town, Wuzhong District, Suzhou 215101, Jiangsu, China.

出版信息

Am J Transl Res. 2024 Sep 15;16(9):4796-4807. doi: 10.62347/XELD8876. eCollection 2024.

Abstract

OBJECTIVE

To evaluate the effectiveness of PVP (PVP) in treating osteoporotic spinal fractures in the elderly and analyze the risk factors for postoperative deep vein thrombosis (DVT) in the lower extremities.

METHODS

A total of 100 elderly patients with osteoporotic spinal fractures, treated between August 2019 and July 2021, were divided into two groups: PVP (research group, n=50) and conservative treatment (control group, n=50). Outcome measures, including injured vertebrae, pain levels, and treatment outcomes, were retrospectively analyzed. Patients who underwent PVPs were further categorized based on the presence of lower extremity DVT one month post-surgery. Logistic regression analysis was used to identify risk factors for post-surgical lower limb DVT.

RESULTS

PVP resulted in a significantly smaller posterior convexity angle of the injured spine and higher anterior, midline, and posterior edges of the injured spine compared to conservative treatment (P<0.001). Patients in the research group had significantly lower visual analogue scale (VAS) scores and higher treatment efficiency compared to those in the conservative treatment group (all P<0.05). Nine cases of lower extremity DVT were observed after PVP. Logistic regression analysis identified age, body mass, smoking, and diabetes as independent risk factors for post-surgical lower extremity DVT.

CONCLUSION

PVP improves spinal function and relieves pain in elderly patients with osteoporotic fractures. However, age, body mass, smoking, and diabetes are independent risk factors for postoperative lower extremity DVT.

摘要

目的

评估经皮椎体成形术(PVP)治疗老年骨质疏松性脊柱骨折的有效性,并分析术后下肢深静脉血栓形成(DVT)的危险因素。

方法

选取2019年8月至2021年7月间接受治疗的100例老年骨质疏松性脊柱骨折患者,分为两组:PVP组(研究组,n = 50)和保守治疗组(对照组,n = 50)。回顾性分析包括受伤椎体、疼痛程度和治疗效果等结局指标。接受PVP治疗的患者在术后1个月根据是否存在下肢DVT进一步分类。采用Logistic回归分析确定术后下肢DVT的危险因素。

结果

与保守治疗相比,PVP导致受伤脊柱的后凸角明显更小,受伤脊柱的前缘、中线和后缘更高(P < 0.001)。研究组患者的视觉模拟评分(VAS)显著低于保守治疗组,治疗有效率更高(均P < 0.05)。PVP术后观察到9例下肢DVT。Logistic回归分析确定年龄、体重、吸烟和糖尿病是术后下肢DVT的独立危险因素。

结论

PVP可改善老年骨质疏松性骨折患者的脊柱功能并缓解疼痛。然而,年龄、体重、吸烟和糖尿病是术后下肢DVT 的独立危险因素。

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