Cone E J, Menchen S L
Addiction Research Center, NIDA, Baltimore, Maryland 21224.
J Anal Toxicol. 1987 Nov-Dec;11(6):276-7. doi: 10.1093/jat/11.6.276.
The validity of the Quik Test Drug Screen for detection of benzoylecgonine was assessed by testing, in random order under blind conditions, 50 aliquots of drug-free urine and 50 aliquots of urine containing 6000 ng/mL of benzoylecgonine. Three independent readers of the test results had an average overall accuracy of only 50%. Each specimen also was tested by TDx assay for cocaine metabolite. In contrast to the Quik Test, the TDx assay was completely accurate. The false positive and false negative rates of the Quik Test Drug Screen for benzoylecgonine in urine were found to be unacceptably high, and its use in urine testing for cocaine abuse is not recommended.
通过在盲法条件下随机顺序检测50份不含药物的尿液样本和50份含有6000 ng/mL苯甲酰爱康宁的尿液样本，评估了Quik Test药物筛查检测苯甲酰爱康宁的有效性。三位独立的检测结果阅读者的总体平均准确率仅为50%。每个样本还通过TDx分析法检测可卡因代谢物。与Quik Test不同，TDx分析法完全准确。发现Quik Test药物筛查对尿液中苯甲酰爱康宁的假阳性和假阴性率高得令人无法接受，不建议将其用于可卡因滥用的尿液检测。
