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新冠病毒感染后急性小脑炎:病例报告及文献复习。

Acute cerebellitis following SARS-CoV-2 infection: A case report and review of the literature.

机构信息

Department of Neurology, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, West Virginia, USA.

Department of Neuroradiology, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, West Virginia, USA.

出版信息

J Med Virol. 2021 Dec;93(12):6818-6821. doi: 10.1002/jmv.27232. Epub 2021 Aug 5.

Abstract

Novel coronavirus disease (COVID-19) first described in Wuhan, China in December 2019, has rapidly spread across the world and become a global public health emergency. Literature on the neurological manifestations of COVID-19 is limited. We report a 24-year-old male, who presented with vertigo, dysarthria, and bradyphrenia 3 weeks after being diagnosed with COVID-19 on nasopharyngeal reverse transcription polymerase chain reaction. The patient was diagnosed with acute cerebellitis based on magnetic resonance imaging features and showed improvement posttreatment with intravenous methylprednisone for 5 days. The scope of this article is to highlight the importance of early identification of neurological symptoms and timely management as the outcomes may be catastrophic.

摘要

2019 年 12 月,在中国武汉首次描述了新型冠状病毒病(COVID-19),该病毒迅速在全球范围内传播,成为全球公共卫生紧急事件。有关 COVID-19 的神经系统表现的文献有限。我们报告了一例 24 岁男性患者,他在鼻咽逆转录聚合酶链反应(RT-PCR)诊断为 COVID-19 3 周后出现眩晕、构音障碍和思维迟缓。根据磁共振成像(MRI)特征,该患者被诊断为急性小脑炎,并在静脉注射甲基强的松龙治疗 5 天后症状改善。本文的目的是强调早期识别神经系统症状和及时治疗的重要性,因为其结果可能是灾难性的。

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