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一名遗传性出血性毛细血管扩张症患者的肺动静脉畸形与栓塞性心肌梗死

Pulmonary Arteriovenous Malformation and Embolic Myocardial Infarction in a Patient With Hereditary Hemorrhagic Telangiectasia.

作者信息

Sánchez-Fernández Gabriel, García-López Fernando, Martínez-Bendayán Isaac, Bello-Peón María José, Marzoa-Rivas Raquel

机构信息

Department of Cardiology, Hospital Universitario Arquitecto Marcide, Ferrol, Spain.

Department of Cardiology, Hospital Universitario de A Coruña, A Coruña, Spain.

出版信息

JACC Case Rep. 2020 Feb 19;2(2):316-318. doi: 10.1016/j.jaccas.2019.11.046. eCollection 2020 Feb.

DOI:10.1016/j.jaccas.2019.11.046
PMID:34317232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8298302/
Abstract

This report describes a case of embolic myocardial infarction secondary to a pulmonary arteriovenous malformation. Pulmonary arteriovenous malformations are rare and mostly congenital and are inherited as an autosomal dominant disorder known as hereditary hemorrhagic telangiectasia. Myocardial infarction is an uncommon complication in patients with untreated pulmonary arteriovenous malformations. ().

摘要

本报告描述了一例继发于肺动静脉畸形的栓塞性心肌梗死病例。肺动静脉畸形较为罕见，大多为先天性，以常染色体显性遗传病形式遗传，即遗传性出血性毛细血管扩张症。心肌梗死在未经治疗的肺动静脉畸形患者中是一种罕见的并发症。（）

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f3/8298302/e2c2e67e4c0b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f3/8298302/634e3647856d/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f3/8298302/e2c2e67e4c0b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f3/8298302/634e3647856d/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f3/8298302/e2c2e67e4c0b/gr1.jpg

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本文引用的文献

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Paradoxical coronary embolisms as a presentation of hereditary hemorrhagic telangiectasia.反常性冠状动脉栓塞作为遗传性出血性毛细血管扩张症的一种表现形式。
J Am Coll Cardiol. 2014 Jan 28;63(3):e5. doi: 10.1016/j.jacc.2013.07.114. Epub 2013 Nov 13.
2
International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia.国际遗传性出血性毛细血管扩张症诊断和管理指南。
J Med Genet. 2011 Feb;48(2):73-87. doi: 10.1136/jmg.2009.069013. Epub 2009 Jun 23.
遗传性出血性毛细血管扩张症表现为无症状性肝病变和早发性心肌梗死及多发颅内动脉瘤病史。
Intern Med. 2023 Feb 15;62(4):553-557. doi: 10.2169/internalmedicine.9259-22. Epub 2022 Jul 29.