Packer S
Department of Surgery (Ophthalmology), North Shore University Hospital, Manhasset, NY 11030.
Ophthalmology. 1987 Dec;94(12):1621-6. doi: 10.1016/s0161-6420(87)33241-5.
Twenty-eight cases of posterior choroidal melanoma were treated with iodine-125 in gold eye plaques. Eleven cases were located within 3.0 mm of the optic nerve (group A), nine were within 3.0 mm of the fovea (group B), and eight were within 3.0 mm of the optic nerve and fovea (group C). The mean follow-up of group A was 46.3 months; group B, 25.5 months; and group C, 42.7 months. Complications included macular edema, cataract and tumor growth. Visual acuity remained within two lines of that tested preoperatively for 4 of 11 patients in group A, 4 of 9 in group B, and 5 of 8 in group C. These results with iodine-125 suggest it as an appropriate treatment for patients with choroidal melanoma located near optic nerve and/or macula.
28例脉络膜后黑色素瘤患者接受了碘-125金标眼贴治疗。11例位于距视神经3.0 mm范围内（A组），9例位于距黄斑3.0 mm范围内（B组），8例位于距视神经和黄斑3.0 mm范围内（C组）。A组的平均随访时间为46.3个月；B组为25.5个月；C组为42.7个月。并发症包括黄斑水肿、白内障和肿瘤生长。A组11例患者中有4例、B组9例中有4例、C组8例中有5例的视力保持在术前测试视力的两行以内。碘-125的这些结果表明，它是治疗位于视神经和/或黄斑附近的脉络膜黑色素瘤患者的一种合适治疗方法。
