Archer D B, Amoaku W M, Kelly G
Department of Ophthalmology, Queen's University of Belfast, Eye and Ear Clinic, Royal Victoria Hospital, Northern Ireland.
Br J Ophthalmol. 1993 Feb;77(2):95-9. doi: 10.1136/bjo.77.2.95.
Two patients who developed localised radiation retinopathy many years after brachytherapy for retinoblastoma are described. In both patients extracapsular cataract extraction and YAG laser capsulotomy were followed by preretinal and vitreous haemorrhage and in one patient there was deterioration of existing radiation retinopathy with macular oedema. Premacular and vitreous haemorrhage occurred from focal, preretinal neovascular membranes which appeared to originate from residual choroidal vascular radicals. Laser photocoagulation was successful in ablating preretinal neovascular membranes and limiting the extent of macular oedema from incompetent retinal capillaries adjacent to the atrophic macular scars.
本文描述了两名视网膜母细胞瘤患者在近距离放射治疗多年后发生局限性放射性视网膜病变的情况。两名患者在进行囊外白内障摘除术和钇铝石榴石激光晶状体囊切开术后均出现视网膜前和玻璃体出血，其中一名患者现有的放射性视网膜病变伴有黄斑水肿，病情恶化。黄斑前和玻璃体出血源于局限性视网膜前新生血管膜，这些新生血管膜似乎起源于残留的脉络膜血管残端。激光光凝成功地消除了视网膜前新生血管膜，并限制了与萎缩性黄斑瘢痕相邻的无功能视网膜毛细血管引起的黄斑水肿范围。
