Department of Internal Medicine, St. Luke's Hospital, Chesterfield.
John T. Milliken Department of Medicine, Division of Gastroenterology, Washington University School of Medicine in Saint Louis, St. Louis, MO.
J Clin Gastroenterol. 2022 Aug 1;56(7):576-583. doi: 10.1097/MCG.0000000000001596. Epub 2021 Jul 28.
The aim was to investigate the impact of night-time emergency department (ED) presentation on outcomes of patients admitted for acute upper gastrointestinal hemorrhage (UGIH).
The relationship between time of ED presentation and outcomes of gastrointestinal hemorrhage is unclear.
Using the 2016 and 2017 Florida State Inpatient Databases which provide times of ED arrival, we identified and categorized adults hospitalized for UGIH to daytime (07:00 to 18:59 h) and night-time (19:00 to 06:59 h) based on the time of ED presentation. We matched both groups with propensity scores, and assessed their clinical outcomes including all-cause in-hospital mortality, in-hospital endoscopy utilization, length of stay (LOS), total hospitalization costs, and 30-day all-cause readmission rates.
Of the identified 38,114 patients with UGIH, 89.4% (n=34,068) had acute nonvariceal hemorrhage (ANVH), while 10.6% (n=4046) had acute variceal hemorrhage (AVH). Compared with daytime patients, ANVH patients admitted at night-time had higher odds of in-hospital mortality (odds ratio: 1.32; 95% confidence interval: 1.06-1.60), lower odds of in-patient endoscopy (odds ratio: 0.83; 95% confidence interval: 0.77-0.90), higher total hospital costs ($9911 vs. $9545, P <0.016), but similar LOS and readmission rates. Night-time AVH patients had a shorter LOS (5.4 vs. 5.8 d, P =0.045) but similar mortality rates, endoscopic utilization, total hospitalization costs, and readmission rates as daytime patients.
Patients arriving in the ED at night-time with ANVH had worse outcomes (mortality, hospitalization costs, and endoscopy utilization) compared with daytime patients. However, those with AVH had comparable outcomes irrespective of ED arrival time.
研究夜间急诊科就诊对急性上消化道出血(UGIH)患者住院结局的影响。
急诊科就诊时间与胃肠道出血结局之间的关系尚不清楚。
利用 2016 年和 2017 年佛罗里达州住院患者数据库,该数据库提供急诊科到达时间,我们根据急诊科就诊时间,将因 UGIH 住院的成年人分为白天(07:00 至 18:59 小时)和夜间(19:00 至 06:59 小时)。我们对两组进行倾向评分匹配,并评估其临床结局,包括全因住院死亡率、住院内镜使用率、住院时间(LOS)、总住院费用和 30 天全因再入院率。
在所确定的 38114 例 UGIH 患者中,89.4%(n=34068)为急性非静脉曲张性出血(ANVH),10.6%(n=4046)为急性静脉曲张性出血(AVH)。与白天就诊的患者相比,夜间就诊的 ANVH 患者住院死亡率更高(比值比:1.32;95%置信区间:1.06-1.60),住院内镜使用率更低(比值比:0.83;95%置信区间:0.77-0.90),总住院费用更高($9911 比 $9545,P<0.016),但 LOS 和再入院率相似。夜间就诊的 AVH 患者 LOS 更短(5.4 比 5.8 天,P=0.045),但死亡率、内镜使用率、总住院费用和再入院率与白天就诊的患者相似。
夜间急诊科就诊的 ANVH 患者与白天就诊的患者相比,预后较差(死亡率、住院费用和内镜使用率)。然而,无论 ED 到达时间如何,AVH 患者的结局相似。