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无症状受试者颈椎曲度康复后中枢传导时间和神经可塑性变化的演示:一项随机、安慰剂对照试验。

Demonstration of central conduction time and neuroplastic changes after cervical lordosis rehabilitation in asymptomatic subjects: a randomized, placebo-controlled trial.

机构信息

Department of Physiotherapy, College of Health Sciences, University of Sharjah, Sharjah, UAE.

Basic Science Department, Faculty of Physical Therapy, Cairo University, Giza, Egypt.

出版信息

Sci Rep. 2021 Jul 28;11(1):15379. doi: 10.1038/s41598-021-94548-z.

Abstract

A randomized controlled study was conducted to evaluate the effect of rehabilitation of the cervical sagittal configuration on sensorimotor integration and central conduction time in an asymptomatic population. Eighty (32 female) participants with radiographic cervical hypolordosis and anterior head translation posture were randomly assigned to either a control or an experimental group. The experimental group received the Denneroll cervical traction while the control group received a placebo treatment. Interventions were applied 3 × per week for 10 weeks. Outcome measures included radiographic measured anterior head translation distance, cervical lordosis (posterior bodies of C2-C7), central somatosensory conduction time (latency) (N13-N20), and amplitudes of potentials for spinal N13, brainstem P14, parietal N20 and P27, and frontal N30. Outcomes were obtained at: baseline, after 10 weeks of intervention, and at 3 months follow up. After 10 weeks and 3-months, between-group analyses revealed statistically significant differences between the groups for the following measured variables: lordosis C2-C7, anterior head translation, amplitudes of spinal N13, brainstem P14, parietal N20 and P27, frontal N30 potentials (P < 0.001), and conduction time N13-N20 (P = 0.004). Significant correlation between the sagittal alignment and measured variables were found (P < 0.005). These findings indicate restoration of cervical sagittal alignment has a direct influence on the central conduction time in an asymptomatic population.

摘要

一项随机对照研究评估了颈椎矢状位形态的康复对无症状人群感觉运动整合和中枢传导时间的影响。80 名(32 名女性)存在颈椎过度伸展伴头前伸的影像学表现的参与者被随机分配到对照组或实验组。实验组接受 Denneroll 颈椎牵引,对照组接受安慰剂治疗。干预措施每周 3 次,持续 10 周。结果测量包括:影像学上测量的头前伸距离、颈椎前凸(C2-C7 后体)、中枢躯体感觉传导时间(潜伏期)(N13-N20)以及脊髓 N13、脑干 P14、顶叶 N20 和 P27、额叶 N30 电位的振幅。结果在基线、干预 10 周后和 3 个月随访时获得。在 10 周和 3 个月后,组间分析显示,以下测量变量在组间存在统计学显著差异:C2-C7 前凸、头前伸、脊髓 N13、脑干 P14、顶叶 N20 和 P27、额叶 N30 电位的振幅(P<0.001)以及 N13-N20 的传导时间(P=0.004)。还发现矢状位排列与测量变量之间存在显著相关性(P<0.005)。这些发现表明颈椎矢状位排列的恢复对无症状人群的中枢传导时间有直接影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e6/8319301/26b9ed768d11/41598_2021_94548_Fig1_HTML.jpg

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