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长期睡眠质量差对背部相关残疾风险的影响以及身体活动的调节作用。

The effect of long-term poor sleep quality on risk of back-related disability and the modifying role of physical activity.

作者信息

Skarpsno Eivind Schjelderup, Nilsen Tom Ivar Lund, Mork Paul Jarle

机构信息

Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), 7491, Trondheim, Norway.

Department of Neurology and Clinical Neurophysiology, St. Olavs Hospital, Trondheim, Norway.

出版信息

Sci Rep. 2021 Jul 28;11(1):15386. doi: 10.1038/s41598-021-94845-7.

DOI:10.1038/s41598-021-94845-7
PMID:34321561
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8319142/
Abstract

Sleep problems and regular leisure time physical activity (LTPA) are interrelated and have contrasting effects on risk of back pain. However, no studies have investigated the influence of long-term poor sleep quality on risk of back-related disability, or if LTPA modifies this association. The study comprised data on 8601 people who participated in three consecutive surveys over ~ 22 years, and who reported no chronic back pain at the two first surveys. Adjusted risk ratios (RRs) for back-related disability were calculated at the last survey, associated with the joint effect of changes in sleep quality between the two first surveys and meeting physical activity guidelines at the second survey. Compared to people with long-term good sleep, people with long-term poor sleep had nearly twice the risk of back-related disability (RR 1.92, 95% CI 1.48-2.49). There was no statistical interaction between sleep and LTPA but people who reported long-term poor sleep and meeting the physical activity guidelines had 35% lower risk of back-related disability compared to people with same level of sleep problems, but who not met the guidelines. These findings suggest that long-term poor sleep quality contributes to a substantially increased risk of chronic and disabling back pain irrespective of LTPA.

摘要

睡眠问题与规律的休闲时间体力活动(LTPA)相互关联,且对背痛风险有相反的影响。然而,尚无研究调查长期睡眠质量差对背部相关残疾风险的影响,也未研究LTPA是否会改变这种关联。该研究包含了8601人的数据,这些人在约22年的时间里连续参与了三次调查,且在前两次调查中均未报告有慢性背痛。在最后一次调查中计算了与前两次调查之间睡眠质量变化以及第二次调查时符合体力活动指南的联合效应相关的背部相关残疾的调整风险比(RRs)。与长期睡眠良好的人相比,长期睡眠差的人背部相关残疾风险几乎高出一倍(RR 1.92,95%CI 1.48 - 2.49)。睡眠与LTPA之间没有统计学交互作用,但报告长期睡眠差且符合体力活动指南的人相比睡眠问题程度相同但未达到指南要求的人,背部相关残疾风险低35%。这些发现表明,无论LTPA如何,长期睡眠质量差都会导致慢性和致残性背痛风险大幅增加。

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