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雌性松鼠猴作为女性盆底功能障碍研究模型。

Female squirrel monkeys as models for research on women's pelvic floor disorders.

机构信息

Postgraduate Program in Animal Health and Production in Amazonia (PPGSPAA), Federal Rural University of the Amazon (UFRA), Brazil.

Postgraduate Program in Animal and Public Health in the Tropics (PPGSaspt), Federal University of Tocantins (UFT), Brazil.

出版信息

Lab Anim. 2021 Dec;55(6):499-508. doi: 10.1177/00236772211032506. Epub 2021 Jul 29.

Abstract

Animal models enable research on biological phenomena with controlled interventions not possible or ethical in patients. Among species used as experimental models, squirrel monkeys ( genus) are phylogenetically related to humans and are relatively easily managed in captivity. Quadrupedal locomotion of squirrel monkeys resembles most other quadrupedal primates in that they utilize a diagonal sequence/diagonal couplets gait when walking on small branches. However, to assume a bipedal locomotion, the human pelvis has undergone evolutionary changes. Therefore, the pelvic bone morphology is not that similar between the female squirrel monkey and woman, but pelvic floor support structures and impacts of fetal size and malpresentation are similar. Thus, this review explores the pelvic floor support structural characteristics of female squirrel monkeys, especially in relation to childbirth to demonstrate similarities to humans.

摘要

动物模型使研究生物现象成为可能,这些现象在患者身上无法进行或不道德。在被用作实验模型的物种中,松鼠猴(属)与人类在系统发育上有关,并且在圈养中相对容易管理。松鼠猴的四足运动与大多数其他四足灵长类动物相似,因为它们在小树枝上行走时使用对角序列/对角对偶步态。然而,为了采取双足运动,人类的骨盆经历了进化变化。因此,雌性松鼠猴和女性的骨盆形态并不完全相似,但是骨盆底支撑结构以及胎儿大小和胎位不正的影响是相似的。因此,本综述探讨了雌性松鼠猴的骨盆底支撑结构特征,特别是与分娩有关的特征,以证明与人类的相似性。

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