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Is the Immunopeptidome Getting Darker?: A Commentary on the Discussion around Mishto et al., 2019.

作者信息

Purcell Anthony W

机构信息

Department of Biochemistry and Molecular Biology, and Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.

出版信息

Front Immunol. 2021 Jul 13;12:720811. doi: 10.3389/fimmu.2021.720811. eCollection 2021.

DOI:10.3389/fimmu.2021.720811
PMID:34326850
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8315041/
Abstract
摘要

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HLA-I immunopeptidome profiling of human cells infected with high-containment enveloped viruses.高防护包膜病毒感染的人细胞 HLA-I 免疫肽组分析。
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本文引用的文献

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Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics.深度学习提高基于质谱的免疫肽组学的灵敏度。
Nat Commun. 2021 Jun 7;12(1):3346. doi: 10.1038/s41467-021-23713-9.
2
Are There Indeed Spliced Peptides in the Immunopeptidome?免疫肽组中是否确实存在拼接肽?
Mol Cell Proteomics. 2021;20:100099. doi: 10.1016/j.mcpro.2021.100099. Epub 2021 May 20.
3
HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy.HLA 配体图谱:改善基于 T 细胞的癌症免疫疗法的 HLA 呈递肽的良性参考。
J Immunother Cancer. 2021 Apr;9(4). doi: 10.1136/jitc-2020-002071.
4
Isolation of HLA Bound Peptides by Immunoaffinity Capture and Identification by Mass Spectrometry.免疫亲和捕获结合质谱法鉴定 HLA 结合肽。
Curr Protoc. 2021 Mar;1(3):e92. doi: 10.1002/cpz1.92.
5
Identification of bacteria-derived HLA-bound peptides in melanoma.鉴定黑色素瘤中细菌衍生的 HLA 结合肽。
Nature. 2021 Apr;592(7852):138-143. doi: 10.1038/s41586-021-03368-8. Epub 2021 Mar 17.
6
Most non-canonical proteins uniquely populate the proteome or immunopeptidome.大多数非规范蛋白是蛋白质组或免疫肽组所特有的。
Cell Rep. 2021 Mar 9;34(10):108815. doi: 10.1016/j.celrep.2021.108815.
7
Spliced HLA-bound peptides: a Black Swan event in immunology.剪接 HLA 结合肽:免疫学中的黑天鹅事件。
Clin Exp Immunol. 2021 May;204(2):179-188. doi: 10.1111/cei.13589. Epub 2021 Mar 28.
8
Identification of spliced peptides in pancreatic islets uncovers errors leading to false assignments.鉴定胰岛中的拼接肽揭示了导致错误分配的错误。
Proteomics. 2021 Apr;21(7-8):e2000176. doi: 10.1002/pmic.202000176. Epub 2021 Mar 5.
9
Elucidation of the Signatures of Proteasome-Catalyzed Peptide Splicing.解析蛋白酶体催化肽拼接的特征。
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10
Spliced Peptides and Cytokine-Driven Changes in the Immunopeptidome of Melanoma.黑色素瘤免疫肽组中拼接肽和细胞因子驱动的变化。
Cancer Immunol Res. 2020 Oct;8(10):1322-1334. doi: 10.1158/2326-6066.CIR-19-0894. Epub 2020 Sep 16.