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工作场所噪声暴露与年龄相关性听力损失的患病率和 10 年发生率。

Workplace noise exposure and the prevalence and 10-year incidence of age-related hearing loss.

机构信息

Department of Linguistics, Macquarie University, Sydney, NSW, Australia.

Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney, NSW, Australia.

出版信息

PLoS One. 2021 Jul 30;16(7):e0255356. doi: 10.1371/journal.pone.0255356. eCollection 2021.

Abstract

There is paucity of population-based data on occupational noise exposure and risk of age-related hearing loss. Therefore, we assessed cross-sectional and longitudinal associations of past workplace noise exposure with hearing loss in older adults. At baseline, 1923 participants aged 50+ years with audiological and occupational noise exposure data included for analysis. The pure-tone average of frequencies 0.5, 1.0, 2.0 and 4.0 kHz (PTA0.5-4KHz) >25 dB HL in the better ear, established the presence of hearing loss. Participants reported exposure to workplace noise, and the severity and duration of this exposure. Prior occupational noise exposure was associated with a 2-fold increased odds of moderate-to-severe hearing loss: multivariable-adjusted OR 2.35 (95% CI 1.45-3.79). Exposure to workplace noise for >10 years increased the odds of having any hearing loss (OR 2.39, 95% CI 1.37-4.19) and moderate-to-severe hearing loss (OR 6.80, 95% CI 2.97-15.60). Among participants reporting past workplace noise exposure at baseline the 10-year incidence of hearing loss was 35.5% versus 29.1% in those who had no workplace noise exposure. Workplace noise exposure was associated with a greater risk of incident hearing loss during the 10-year follow-up: multivariable-adjusted OR 1.39 (95% CI 1.13-1.71). Prior occupational noise exposure was not associated with hearing loss progression. Workplace noise exposure increased the risk of incident hearing loss in older adults. Our findings underscore the importance of preventive measures which diminish noise exposure in the workplace, which could potentially contribute towards reducing the burden of hearing loss in later life.

摘要

关于职业性噪声暴露与年龄相关性听力损失的关系,目前基于人群的数据还很缺乏。因此,我们评估了既往工作场所噪声暴露与老年人听力损失的横断面和纵向关联。在基线时,纳入了 1923 名年龄在 50 岁以上、有听力和职业性噪声暴露数据的参与者进行分析。在较好耳中,0.5、1.0、2.0 和 4.0 kHz 的纯音平均听阈(PTA0.5-4KHz)>25dBHL 确定存在听力损失。参与者报告了工作场所噪声暴露情况,以及噪声暴露的严重程度和持续时间。既往职业性噪声暴露与中重度听力损失的发生风险增加 2 倍相关:多变量调整后的比值比(OR)为 2.35(95%可信区间 1.45-3.79)。暴露于工作场所噪声>10 年,发生任何听力损失的风险增加(OR 2.39,95%可信区间 1.37-4.19)和中重度听力损失的风险增加(OR 6.80,95%可信区间 2.97-15.60)。在基线时有既往工作场所噪声暴露报告的参与者中,10 年的听力损失发生率为 35.5%,而无工作场所噪声暴露的参与者为 29.1%。在 10 年随访期间,工作场所噪声暴露与听力损失的发生率增加相关:多变量调整后的比值比(OR)为 1.39(95%可信区间 1.13-1.71)。既往职业性噪声暴露与听力损失进展无关。职业性噪声暴露增加了老年人发生听力损失的风险。我们的研究结果强调了在工作场所采取减少噪声暴露的预防措施的重要性,这可能有助于减轻晚年听力损失的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a43/8323918/52c7f130a9f6/pone.0255356.g001.jpg

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