Department of Women's & Newborn Health, Westmead Hospital, Westmead, New South Wales, Australia (Dr Khajehei, Dr Chua, and Mss Gidaszewski and Swain); Westmead Clinical School, The University of Sydney, Sydney, New South Wales, Australia (Dr Khajehei and Ms Gidaszewski); University of New South Wales, Sydney, New South Wales, Australia (Dr Khajehei); and Western Sydney University, Sydney, New South Wales, Australia (Dr Chua).
J Perinat Neonatal Nurs. 2021;35(3):E30-E37. doi: 10.1097/JPN.0000000000000555.
This study aims to evaluate the correlation between the results of transcutaneous bilirubin (TcB) levels measured by the 2 transcutaneous bilirubinometers according to the area tested and to compare the TcB measurements and the serum bilirubin (SBR) levels. We screened 78 neonates born at more than 35 weeks of gestation and aged less than 168 hours for jaundice. We used JM-105 and MBJ-20 to measure the TcB at the forehead and the chest. For newborns who had high TcB measurements, we obtained blood samples during the subsequent 30 minutes. There was a strong correlation between the TcB measurements by JM-105 and MBJ-20 and this correlation was stronger when they were used on the sternum. The mean differences between the TcB measurements on the forehead and the sternum and the SBR levels were similar for the JM-105 and the MBJ-20. There was a strong correlation between SBR and the measurements using the 2 devices on the sternum (JM-105: r = 0.805; MBJ-20: r = 0.801), unlike measurements taken on the forehead by each device (r = 0.777 and r = 0.751, respectively). Both devices had high sensitivity and negative predictive values at SBR level of less than 230 μmol/L (<13.4 mg/dL) and high specificity and positive predictive values at SBR level of 230 μmol/L and greater (>13.4mg/dL). Both devices equally overestimated the actual SBR and had more reliable results if used on the sternum.
本研究旨在评估根据测试区域，使用 2 种经皮胆红素仪（TcB）测量结果之间的相关性，并比较 TcB 测量值与血清胆红素（SBR）水平。我们对 78 例胎龄超过 35 周且年龄小于 168 小时的新生儿进行筛查，以发现黄疸。我们使用 JM-105 和 MBJ-20 在额头和胸部测量 TcB。对于 TcB 测量值较高的新生儿，我们在随后的 30 分钟内采集血样。JM-105 和 MBJ-20 的 TcB 测量值之间存在很强的相关性，当在胸骨上使用时，这种相关性更强。JM-105 和 MBJ-20 在额头和胸骨上的 TcB 测量值与 SBR 水平之间的平均差异相似。SBR 与 2 种仪器在胸骨上的测量值之间存在很强的相关性（JM-105：r = 0.805；MBJ-20：r = 0.801），而与每个仪器在额头上的测量值相关性不同（r = 0.777 和 r = 0.751）。两种仪器在 SBR 水平低于 230 μmol/L（<13.4mg/dL）时具有高灵敏度和阴性预测值，在 SBR 水平为 230 μmol/L 及以上时具有高特异性和阳性预测值。两种仪器都高估了实际的 SBR，并且在胸骨上使用时结果更可靠。
