Students' Research Committee, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Exp Med Biol. 2021;1291:121-137. doi: 10.1007/978-3-030-56153-6_7.
Curcumin is an active molecule present in turmeric and is the main therapeutic compound. There is growing evidence that curcumin could affect various anthropometric indices. We performed a systematic review to evaluate the efficacy of curcumin supplementation on anthropometric indices in obese and overweight individuals.
A comprehensive search was conducted in PubMed, Scopus, Web of Science, and Google Scholar from inception up to February 2020 to identify randomized controlled trials investigating the effect of curcumin supplementation on anthropometric indices including body weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), arm circumference (AC), waist-hip ratio (WHR), total body fat (TBF), and visceral fat (VF) in obese and overweight individuals. The Jadad scale was used to assess the quality of the included studies.
Twenty-eight randomized controlled trials, comprising 2168 participants, were included in the systematic review. The results of 16 papers indicated that curcumin reduced at least one of the anthropometric indices among individuals with a BMI ≥ 25 kg/m. Nevertheless, 12 articles showed that curcumin supplementation was not effective in any of the measured anthropometric factors. The included trials exhibited substantial heterogeneity in terms of the treatment protocol, follow-up duration, curcumin dosage, and background diseases of the participants.
Clinical trials that have independently examined the effects of curcumin in obese or overweight individuals are limited. However, available studies indicate that curcumin has beneficial impacts on various anthropometric indices. Further trials with longer duration of interventions are needed to confirm these findings.
姜黄素是姜黄中的一种活性分子，也是主要的治疗化合物。越来越多的证据表明，姜黄素可能会影响各种人体测量学指标。我们进行了一项系统评价，以评估姜黄补充剂对肥胖和超重个体人体测量学指标的疗效。
从建库起至 2020 年 2 月，我们在 PubMed、Scopus、Web of Science 和 Google Scholar 上全面检索了评估姜黄补充剂对肥胖和超重个体人体测量学指标（包括体重、体重指数（BMI）、腰围（WC）、臀围（HC）、臂围（AC）、腰臀比（WHR）、总体脂肪（TBF）和内脏脂肪（VF）的影响的随机对照试验。我们使用 Jadad 量表评估纳入研究的质量。
系统评价纳入了 28 项随机对照试验，共 2168 名参与者。16 篇论文的结果表明，姜黄降低了 BMI≥25 kg/m 2 个体的至少一种人体测量学指标。然而，12 篇文章表明，姜黄补充剂在任何测量的人体测量学因素方面都没有效果。纳入的试验在治疗方案、随访时间、姜黄剂量和参与者的基础疾病方面存在很大的异质性。
独立评估姜黄对肥胖或超重个体影响的临床试验有限。然而，现有研究表明，姜黄对各种人体测量学指标有有益的影响。需要进行持续时间更长的试验来证实这些发现。
Zotero 插件