a Department of Basic Medical Sciences , Neyshabur University of Medical Sciences , Neyshabur , Iran.
b Food Security Research Center , Isfahan University of Medical Sciences , Isfahan , Iran.
J Am Coll Nutr. 2018 Mar-Apr;37(3):215-222. doi: 10.1080/07315724.2017.1392263. Epub 2018 Jan 9.
Curcumin is an active constituent of turmeric. Recently, scientists have suggested that curcumin can be used in weight reduction. We performed a systematic review based on randomized controlled trials to assess the effects of curcumin supplementation on anthropometric variables.
We searched databases including PubMed, Embase, Web of Science, Scopus, and Google Scholar up to August 2017. Randomized clinical trials assessing the effects of curcumin on anthropometric parameters in human adults were included.
Eight randomized clinical trials were allowed to be included in the systematic review. Five articles used the regular form of curcumin with short follow-up duration and did not indicate any significant effect on anthropometric measures, while three articles with significant results used either the more bioavailable form of curcumin or a longer intervention duration.
Randomized clinical trials related to curcumin effect on weight are limited but their result indicated useful effect of curcumin on weight. It seems that the bioavailable form of curcumin can reduce obesity and overweight. Further articles with longer duration of intervention and different forms of curcumin supplementation are necessary before any recommendation is made for clinical use of these interventions.
姜黄素是姜黄的一种活性成分。最近，科学家们提出姜黄素可用于减肥。我们进行了一项系统评价，基于随机对照试验来评估姜黄素补充对人体测量变量的影响。
我们检索了包括 PubMed、Embase、Web of Science、Scopus 和 Google Scholar 在内的数据库，检索时间截至 2017 年 8 月。纳入评估姜黄素对成年人人体测量参数影响的随机临床试验。
八项随机临床试验被允许纳入系统评价。五篇文章使用常规形式的姜黄，随访时间短，未表明对人体测量指标有任何显著影响，而三篇有显著结果的文章使用了更具生物利用度的姜黄形式或更长的干预时间。
与姜黄素对体重影响相关的随机临床试验有限，但结果表明姜黄素对体重有有益的影响。似乎姜黄素的生物利用形式可以减轻肥胖和超重。在推荐这些干预措施用于临床应用之前，需要进行具有更长干预时间和不同形式姜黄素补充的进一步研究。
