Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan; Japanese Research Group for Urinary Tract Infection (JRGU), 1-1 Mukogawa-machi, Nishinomiya, 663-8501, Japan.
Department of Urology, Federation of National Public Services and Affiliated Personnel Mutual Aid Associations, Shin-Kokura Hospital, Kanada 1-3-1, Kokurakita-ku, Kitakyusyu, 803-0816, Japan; Japanese Research Group for Urinary Tract Infection (JRGU), 1-1 Mukogawa-machi, Nishinomiya, 663-8501, Japan.
J Infect Chemother. 2021 Oct;27(10):1384-1388. doi: 10.1016/j.jiac.2021.07.007. Epub 2021 Jul 28.
Non-chlamydial non-gonococcal urethritis (NCNGU) is defined as urethritis with neither Neisseria gonorrhoeae nor Chlamydia trachomatis. Possible causative agents of NCNGU include Mycoplasma genitalium, Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis, Trichomonas vaginalis, and so on. Among these microorganisms, the pathogenicity of M. genitalium and T. vaginalis to the male urethra has been confirmed so far. The Asian Association of Urinary Tract Infection and Sexually Transmitted Infection (AAUS) belonging to the Urological Association of Asia (UAA) had developed the guidelines regarding NCNGU and the present guidelines were updated from previous edition. Relevant references were meticulously reviewed again and latest studies were collected. In addition to the levels of evidence, the recommendation grades were defined using the modified GRADE methodology. Herein, we present the new edition of the UAA-AAUS guidelines for M. genitalium and non-chlamydial non-gonococcal urethritis.
非淋球菌性尿道炎（NCNGU）的定义为既没有淋病奈瑟菌也没有沙眼衣原体的尿道炎。NCNGU 的可能病原体包括生殖支原体、解脲脲原体、微小脲原体、人型支原体、阴道毛滴虫等。在这些微生物中，目前已经证实生殖支原体和阴道毛滴虫对男性尿道具有致病性。亚洲尿路感染和性传播感染协会（AAUS）隶属于亚洲泌尿外科学会（UAA），已经制定了 NCNGU 指南，本指南是对上一版的更新。再次仔细审查了相关参考文献并收集了最新研究。除了证据水平外，还使用改良的 GRADE 方法定义了推荐等级。在此，我们提出了 UAA-AAUS 生殖支原体和非淋球菌性非淋菌性尿道炎指南的新版本。
